CHRISTOPHER J. LETTIERI, MD, FACP, FCCP, FAASM
Colonel, Medical Corps, U.S. Army (Ret) Pulmonary, Critical Care, and Sleep Medicine Professor of Medicine, Uniformed Services University
Education
2004 – 2005 Fellowship, Sleep Medicine, Walter Reed Army Medical Center, Washington DC
2002 – 2006 Fellowship, Pulmonary & Critical Care Medicine, Walter Reed Army Medical Center
1998 – 2001 Residency, Internal Medicine, Tripler Army Medical Center, Honolulu, Hawaii
1998 – 1999 Internship, Transitional, Tripler Army Medical Center, Honolulu, Hawaii
1994 – 1998 Doctor of Medicine – Uniformed Services University of the Health Sciences
1990 – 1994 Bachelor of Science – Molecular and Cellular Biology, University of Arizona,
CURRENT BOARDS AND APPOINTMENTS
2018 – GlaxoSmithKline, Respiratory Disease Expert, US Medical Affairs
2015 – Government Affairs Committee: National Sleep Foundation
2015 – Board of Trustees: Browne Academy
2015 – Advisory Board: American Academy of Cardiovascular Sleep Medicine
FACULTY APPOINTMENTS
2012 – Professor of Medicine, Uniformed Services University
2010 – 2012 Clinical Assistant Professor of Medicine, Georgetown University
2007 – 2012 Associate Professor of Medicine, Uniformed Services University
2001 – 2007 Assistant Professor of Medicine, Uniformed Services University
PREVIOUS LEADERSHIP ASSIGNMENTS
2016 – 2018 Medical Director, Global Health and Clinical Operations, Office of the Joint Staff Surgeon
2016 – 2018 Senior Medical Advisor to the Joint Chiefs of Staff
2014 – 2018 Pulmonary/Critical Care Medicine Consultant to the Army Surgeon General
2006 – 2018 Key Faculty, Pulmonary, Critical Care, & Sleep Medicine Fellowships, NCC
2009 – 2015 Program Director, Sleep Medicine Fellowship, National Capital Consortium
2014 Chief of Medicine, 31st Combat Support Hospital, Operation Enduring Freedom, Afghanistan
2012 – 2014 Assistant Deputy Commander/Deputy Director for Medical Services, Walter Reed
2013 Battalion Surgeon, 18th Infantry Regiment, 1st Infantry Div, Operation Shared Accord, Africa
2011 – 2013 Chief, Sleep Disorders Center, Walter Reed National Military Medical Center
2007 – 2012 Chief & Medical Director, Sleep Medicine, Walter Reed Army Medical Center
2007 – 2009 Medical Director, Invasive Procedures and Bronchoscopy Suite
2006 – 2007 Chief of Critical Care, 14th Combat Support Hospital, Operation Enduring Freedom, Afghanistan
2001 – 2002 Chief of Medical Residents – Department of Medicine, Tripler Army Medical Center
PREVIOUS BOARDS, APPOINTMENTS, AND COMMITTEES
2017 – 2018 Chair, Health Policy Strategy Presidential Committee, American Academy of Sleep Medicine
2016 – 2018 Board Member/Medical Advisor: American Board of Dental Sleep Medicine
2014 – 2018 Food & Drug Administration Advisory Committee: Anesthesiology & Respiratory Devices
2014 – 2015 Medical Safety Review Board, Medimmune Inc
2010 – 2012 Chair, Education Committee, American Academy of Sleep Medicine
2010 – 2012 Executive Committee, American Sleep Medicine Foundation
2008 – 2009 Program Committee, Environmental and Occupational Health, American Thoracic Society
2006 – 2009 Steering Committee, Disaster Medicine, American College of Chest Physicians
2005 – 2008 Chair, Terrorism and Disaster Medicine, American Thoracic Society
PREVIOUS PROFESSIONAL ASSIGNMENTS (MILITARY)
2016 – 2018 Chair: Forward Resuscitative Care in Dispersed Operations, Capability Based Assessment
2016 – 2018 Co-Chair and Critical Care Medicine Champion: Knowledge, Skills and Abilities Reformation
2016 – 2018 Executive Committee: Armed Services Biomedical Research Evaluation and Management
2016 – 2018 Lead: National Defense Authorization Act – Trauma Management Implementation Plan
2016 – 2018 Co-Chair: DoD Trauma Enterprise, Capability Based Assessment
2007 – 2012 Research Coordinator, Internal Medicine Residency, Department of Medicine, Walter Reed
2007 – 2012 Key Faculty Member, Internal Medicine, Walter Reed Army Medical Center
2003 – 2012 Medical Education Committee, Department of Medicine, Walter Reed.
2008 – 2009 Associate Program Director, Sleep Medicine Fellowship, National Capital Consortium
2007 – 2009 Performance Improvement Representative, Department of Medicine, Walter Reed
2001 – 2002 CPR Committee, Tripler Army Medical Center.
2001 – 2002 Medical Records Review Committee, Tripler Army Medical Center.
2001 – 2002 Institutional Coordination Committee, Tripler Army Medical Center.
2001 – 2002 4th Year Medical Student Clerkship Coordinator, Tripler Army Medical Center.
2000 – 2002 Department of Medicine Education Committee, Tripler Army Medical Center.
1999 – 2002 Peer Review Assessment Team, Tripler Army Medical Center.
2000 – 2001 Prevention and Control of Infectious Diseases Committee, Tripler Army Medical Center.
2000 Assistant Operations Officer, Operation Tendon Mondial, Mongolia
1998 – 1999 Transitional Intern Representative, Tripler Amy Medical Center
RESEARCH CONSORTIA AND TASK FORCES
2017 – 2018 Army STARRS study group: Sleep Disorders
2015 – Member, Sleep Disorders and Traumatic Brain Injury Advisory Committee
2014 – Oral Appliance Network for Global Effectiveness (ORANGE International Study Group)
2015 – 2018 Idiopathic Pulmonary Fibrosis, TOC Advisory Board, Prime Education
2014 – 2017 Clinical Practice Guideline Committee: “The Role of Weight Management in the Treatment of Adult Obstructive Sleep Apnea” American Thoracic Society
2012 – 2015 Clinical Practice Guideline Committee: “Treatment of Obstructive Sleep Apnea and Snoring with Oral Appliance Therapy” American Academy of Sleep Medicine
2007 – 2010 CPAP Promotion And Prognosis – the Army Sleep Apnea Program (CPAP ASAP) Study Group
MILITARY TRAINING AND EDUCATION
2016
Executive Medicine Leadership Course
2010
U.S. Army Command and General Staff College – Intermediate Level Education
2006
Emergency War Surgery Course
2006
U.S. Army Captains Career Course (Advanced Officer Leadership Course)
2001
Medical Management of Chemical and Biological Casualties Course
1997
USUHS Combat Casualty Care Course, Operation Bushmaster
1994
U.S. Army Officer Basic Leadership Course, Medical/Dental Corps
1993
NCO Academy – Primary Leadership Development Course. Commandant’s List
1993
Nuclear/Biological/Chemical Specialist Course
1993
Counter Narcotics and Tactical Operations Medical Specialist (CONTOMS)
1993
Emergency Medical Technician – Tactical
1992
Emergency Medical Technician – Wilderness
1991
Emergency Medical Technician – Intermediate
1991
Medical Specialist, 91B. Distinguished Honor Graduate
1990
Basic Combat Training. Honor Graduate
SYMPOSIA AND GRADUATE COURSE LEADERSHIP
2018
Co-Chair, Sleep for Life, Conference of the American Academy of Cardiovascular Sleep Medicine
2017
Co-Chair, Sleep Medicine Collaboration Conference
2016
Course Director, Annual Conference of the Academy of Clinical Sleep Disorders Disciplines
2013
Planning Committee, Kenneth L. Artiss Symposium
2012
Chair, TriService Conference of the American College of Physicians, Military Chapters
2010
Seminar Chair, Uniformed Services American Family Physicians Conference
2008
Symposium Chair, Disaster Medicine. American College of Chest Physicians
2008
Symposium Chair, Pulmonary and Critical Care During Catastrophes. American Thoracic Society
2007
Course Director, Best Practices of ICU Disaster Plans: American College of Chest Physicians
2006
Symposium Chair, Medical Response to Disasters. American Thoracic Society
2006
Course Director, Pulmonary and Critical Care During Catastrophes. American Thoracic Society
PROFESSIONAL SOCIETIES
American College of Physicians (FACP)
Associate, 2000-2003; Member, 2003-2008; Fellow, 2008
Meeting Chair, 2012
American College of Chest Physicians (FCCP)
Affiliate, 2002-2006; Member, 2006-2007; Fellow, 2007
Steering Committee Member, 2006–2009
Post Graduate Course Chair, 2007, 2008
American Academy of Sleep Medicine (FAASM)
Member, 2004-2007; Fellow, 2007
Education Committee, Chair 2010-2012, Member, 2009-2010
Task Force Member, 2012–2015
Chair, Health Policy Strategy Presidential Committee, 2017 – 2018
American Thoracic Society
Section Chair, Terrorism and Disaster Medicine, 2005–2008
Post Graduate Course Chair, 2006, 2007
Symposium Chair, 2006, 2008
Program Committee Member, Environmental and Occupational Health, 2008 – 2009
Task Force Member, 2014–2017
American Academy of Cardiovascular Sleep Medicine
Advisory Board; 2015 – Present
Course Director: 2017
EDITORIAL ACTIVITIES
2017 – 2018 Section Editor, Sleep Perspectives, CHEST Physician
2016 – Present Associate Editor, Sleep and Breathing
2012 – Present Editorial Board, Journal of Dental Sleep Medicine
2010 – 2016 Editorial Board, Sleep and Breathing
2008 – 2017 Editorial Board, Pulmonary Medicine, MedScape
2005 – 2017 Editorial Board, Critical Care Medicine, MedScape
2006 – 2009 Editorial Board, Emergency Medicine, MedScape
2008 – Present Peer Reviewer, Annals of Internal Medicine
2008 – Present Peer Reviewer, American Journal of Respiratory and Critical Care Medicine
2008 – Present Peer Reviewer, Sleep and Breathing
2007 – Present Peer Reviewer, Sleep
2007 – Present Peer Reviewer, European Respiratory Journal
2005 – Present Peer Reviewer, Archives of Internal Medicine and JAMA
2005 – Present Peer Reviewer, Journal of Clinical Sleep Medicine
2004 – Present Peer Reviewer, Chest
2003 – 2007 Peer Reviewer, Journal of Military Medicine
AWARDS AND HONORS
Academic
2014
Induction to Alpha Omega Alpha (AOA) – Maryland Gamma Chapter
2012
Vice Admiral James A. Zimble Award – Outstanding Program Director, National Capital Consortium
2010
Outstanding Teaching Staff, Walter Reed Army Medical Center
2008
Leonard Award for Education in Internal Medicine, Uniformed Services University
2006
Major General Lewis A. Mologne Award, Outstanding Graduate, National Capital Consortium
2005
Outstanding Teaching Fellow, Walter Reed Army Medical Center
2002
Michael K. Yancey Outstanding Staff Clinician Award – Tripler Army Medical Center
2001
Outstanding Resident Teacher Award – Tripler Army Medical Center
2001
Resident Teacher of the Year – Department of Medicine, Tripler Army Medical Center
2000
Outstanding Resident Teacher Award – Tripler Army Medical Center
2000
Resident Teacher of the Year – Department of Medicine, Tripler Army Medical Center
2000
Teacher of the Year - Department of Nursing, Tripler Army Medical Center
1994
Summa Cum Laude with Academic Distinction. Honor Graduate, University of Arizona
Research
2011
Par Sleep Disordered Breathing Research Award – American Sleep Apnea Association
2009
William Crosby Excellence in Research Award – American College of Physicians
2009
Par Sleep Disordered Breathing Research Award – American Sleep Apnea Association
2009
Sleep Disordered Breathing Research Award – American Academy of Sleep Medicine
2009
Robert A Phillips Research Award, National Capital Consortium (1st Place)
2009
Young Investigators Forum Award, Finalist (2 awards)
2008
Young Investigators Award – American College of Chest Physicians
2007
Poster Competition– American College of Physicians, Army Chapter (1st Place)
2006
Scientific Poster, Research –DC Thoracic Society (1st Place)
2006
Scientific Poster, Research –DC Thoracic Society (2nd Place)
2005
Bailey K. Ashford Clinical Research Award (1st Place)
2004
Scientific Poster winner – Interstitial Lung Diseases, American College of Chest Physicians
2003
Young Investigators Award – American College of Chest Physicians
2002
Poster Competition Winner – American College of Physicians, Army Chapter
1994
Student Research Award Foundation Winner – University of Arizona
1994
Capstone Achievement Award Winner – University of Arizona
Department of Defense Military Awards/Medals
Defense Superior Service Medal
Defense Meritorious Service Medal
Meritorious Service Medal (5th award)
Global War on Terrorism Service Medal
NATO ISAF Expeditionary Medal (2nd Award)
OEF Afghanistan Service Medal (3 Combat Stars)
Joint Commendation Medal (2nd award)
NCO Development Ribbon
Army Commendation Medal (8th award)
Army Service Ribbon
Joint Service Achievement Medal
·Army Achievement Medal (4th award)
Overseas Service Ribbon
Joint Meritorious Unit Award
Army Reserves Achievement Medal
Army Superior Unit Award
Army Good Conduct Medal
Army Meritorious Unit Award (2nd award)
National Defense Medal (2nd award)
Order of Military Medical Merit
Other
2011
Army “A” Proficiency Designator
2010
Order of Military Medical Merit recipient
2009
Surgeon General’s Physician Recognition Award
BOARD CERTIFICATION AND SKILL IDENTIFIERS
2015
Clinical Investigation and Research Regulatory Oversight [US Army 8H ASI]
2009
Diplomate, American Board of Internal Medicine – Sleep Medicine [US Army Z3 ASI]
2006, 2016
Diplomate, American Board of Internal Medicine – Critical Care Medicine [US Army M4 ASI]
2005
Diplomate, American Board of Sleep Medicine
2004, 2014
Diplomate, American Board of Internal Medicine – Pulmonary Medicine [US Army 60F9A]
2001, 2011
Diplomate, American Board of Internal Medicine [US Army 61F9B]
PUBLICATIONS: JOURNAL ARTICLES (PEER REVIEWED)
1. Warren WA, Walter RJ, Switzer M, Lettieri CJ. Correlation between positive airway pressure and medication adherence – the healthy user effect. Submitted for publication (under review)
2. Smith PR, Lettieri CJ. Directly referring Atrial Fibrillation patients for polysomnography negatively impacts subsequent positive airway pressure adherence. Submitted for publication (under review)
3. Dombrowsky JW, MD, Lettieri CJ, McCarthy JG, Shah AS, Kelly W, Roop SA, Holley AB. The Prevalence of Erectile Dysfunction and Long-term Impact of CPAP Therapy: A Prospective, Case- Controlled Trial. Submitted for publication (under review)
4. Hudgel DW, Patel SR, Ahasic AM, Barlett SJ, Bessesen D, Coaker M, Flander M, Grunstein R, Kapur V, Gurubhagavataula I, Lettieri CJ, Naughton M, Owens R, Pepin JL, Toumileheto H, Wilson KC. The Role of Weight Management in the Treatment of Adult Obstructive Sleep Apnea - An Official American Thoracic Society Clinical Practice Guideline. Am J Resp Crit Care Med. 2018; 198(6):70-87. [PMID: 30215551]
5. Wickwire E, Schnyer DM, Germain A, Williams S, Lettieri C, McKeon A, Scharf S, Stocker R, Albrecht JS, Badjatia N, Markowitz A, Manley G. Sleep, sleep disorders, and circadian health following mild traumatic brain injury: Review and research agenda. J Neurotrauma. 2018 Nov 15;35(22):2615-2631 [PMID: 29877132]
6. Hudson AJ, Walter RJ, Flynn J, Szpisjak DF, Rodgers M, Capaldi VF, McDuffie B, Lettieri CJ. Ambulatory Surgery Has Minimal Impact on Sleep Parameters: A Prospective Observational Trial. J Clin Sleep Med 2018; 14(4):593-602 [PMID: 29609705]
7. Lettieri CJ, Williams SJ, Collen JF, Wickwire EM. Treatment of Obstructive Sleep Apnea: Achieving Adherence to Positive Airway Pressure Treatment and Dealing with Complications. Sleep Medicine Clinics. 2017; 12(4): 1-14 [PMID: 29108610]
8. Walter RJ, Hagedorn S, Lettieri CJ. Impact of Diagnosing and Treating Obstructive Sleep Apnea on Health Care Utilization. Sleep Medicine. 2017; 38:73-77 [PMID: 29031760]
9. Clark PA, Inocencio RC, Lettieri CJ. ITRACH: Validating a tool for predicting prolonged mechanical ventilation. J Intensive Care Med 2018; e-pub ahead of print [PMID: 27899470]
10. Eliasson AH, Eliasson AH, Lettieri CJ. Differences in sleep habits, study time, and academic performance between US-born and foreign-born college students. Sleep Breath 2017; 21(2):529-533 [PMID: 27696077]
11. Wickwire, EM, Williams SG, Roth T, Capaldi VF, Jaffe M, Moline M, Motamedi GK, Morgan GW, Mysliwiec V, Germain A, Pazdan RM, Ferziger R, Balkin TJ, MacDonald ME, Macek TA, Yochelson MR, Scharf SM, Lettieri CJ. Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group. Neurotherapeutics. 2016; 13(2):403- 17 [PMID: 27002812]
12. Lettieri CJ, Collen JC, Williams SG. Obstructive sleep apnea syndrome and post-traumatic stress disorder: Clinical outcomes and impact of PAP therapy. Chest 2016; 149(2):483-490 [PMID: 26291560]
13. Ramar K, Dort LC, Katz SG, Lettieri CJ, Harod CG, Thomas SM, Chervon RD. Clinical Practice Guidelines for the Treatment of Obstructive Sleep Apnea and Snoring with Oral Appliance Therapy: An Update for 2015. J Clin Sleep Med 2015; 11(7):773-827 [PMID: 26094920]
14. Collen JC, Lettieri CJ, Greenburg DL, Eliasson AH. Postoperative CPAP use impacts long-term weight loss following bariatric surgery. J Clin Sleep Med. 2015; 11:213-217 [PMID: 25515283]
15. Williams SG, Collen JC, Orr N, Holley AB, Lettieri CJ. Sleep Disorders in Combat-Relater Post Traumatic Stress Disorder. Sleep Breath 2015; 19:175-182 [PMID: 24752303]
16. Williams SG, Collen JC, Wickwire E, Lettieri CJ, Mysliwiec V. The Impact of Sleep on Soldier Performance. Curr Psychiatry Rep, 2014; 16:459-462 [PMID: 24942599]
17. Clark P, Lettieri CJ. Clinical model for predicting prolonged mechanical ventilation. J Crit Care 2013; 28:880-887 [PMID: 23683556]
18. Williams SG, Lettieri CJ. Violent behavior during sleep. J Sleep Disorders Ther 2013; 2:1-5
19. Wickwire E, Lettieri CJ, Claims AA, Collop NA. Maximizing Continuous Positive Airway Pressure Adherence in Adults, A Common Sense Approach. Chest 2013; 144:680-693 [PMID: 23918114]
20. Lettieri CJ, Walter RJ. Impact of Group Education on Continuous Positive Airway Pressure Adherence. J Clin Sleep Med 2013; 9:537-41 [PMID: 23772185]
21. Loh J, Lettieri CJ. Loh G, Lettieri C, Shah A. “Bronchial Arterial Embolization for Massive Hemoptysis in Cavitary Sarcoidosis” BMJ Case Rep Jan 25 2013. [PMID: 23355590]
22. Dombrowsky J, Williams SG, Wickwire E, Lettieri CJ. Strategies to Improve CPAP Adherence. Clin Pulm Med. 2012; 20:21-28
23. Collen J, Lettieri C, Hoffman M. The Impact of Post-Traumatic Stress Disorder on CPAP Adherence in Patients with Obstructive Sleep Apnea. J Clin Sleep Med. 2012; 8:667-672 [PMID: 23243400]
24. Williams SG, Correa D, Lesage S, Lettieri CJ. Electroencephalographic hypersynchrony in a child with night terrors. Sleep Breath 2013; 17:465-7 [PMID:22773270]
25. Collen JF, Orr N, Lettieri CJ, Carter KA, Holley AB. Sleep Disturbances Among Soldiers With Combat- Related Traumatic Brain Injury. Chest. 2012; 142:622-30 [PMID:22459784]
26. Williams SG, Lettieri CJ, Dombrowsky J. CPAP: Enhancing Its Use. Sleep Medicine: Current Respiratory Care Reports. 2012; 1:131-138
27. Lettieri CJ, Paolino N, Holley AB, Shah AA, Eliasson AH. A Comparison of Adjustable and Non- Adjustable Oral Appliances for the Treatment of Obstructive Sleep Apnea. J Clin Sleep Med. 2011; 7:439- 45 [PMID:22003337]
28. Holley AB, Lettieri CJ, Shah AA. Efficacy of An Adjustable Oral Appliance and Comparison to Continuous Positive Airway Pressure for the Treatment of Obstructive Sleep Apnea Syndrome. Chest. 2011;140: 1511-6 [PMID:21636666]
29. Dombrowsky J, Lettieri CJ. Eszopiclone in the management of insomnia among the elderly. Clinical Medicine Insights: Geriatrics. 2011; 4:1-8
30. Lettieri CF, Lettieri CJ, Carter KA. Does Home Sleep Testing Impair CPAP compliance in Patients with Obstructive Sleep Apnea? Chest. 2011; 139:849-54 [PMID:21292757]
31. Carter KC, Lettieri CJ, Pena JM. An unusual cause of insomnia following IED-induced traumatic brain injury. J Clin Sleep Med. 2010; 15:205-206 [PMID:20411701]
32. Cheezum M, Lettieri CJ. Obstructive Sleep Apnea presenting as a pseudopheochromocytoma. J Clin Sleep Med. 2010; 15:190-191 [PMID:20411698]
33. Sherestha M, Shah AA, Lettieri CJ. Dyspnea and dysentery: a case report of pleuropulmonary amebiasis.
South Med J. 2010; 103:165-8 [PMID:20175253]
34. Collen J, Holley AB, Lettieri CJ, Kelly W, Roop S. The Impact of Split-night versus Traditional Sleep Studies on CPAP Compliance. Sleep Breath. 2010; 14:93-9 [PMID: 19714379]
35. Eliasson AH, Lettieri CJ, Eliasson A. Sleep Habits and Academic Performance in College Students.
Sleep Breath. 2010; 14:71-5 [PMID: 19603214]
36. Lettieri CJ, Shah AA, Holley AB, Kelly WB, Chang AS, Roop SA. Effects of a Short Course of Eszopiclone Improves CPAP Adherence: A Randomized Trial. Ann Int Med. 2009; 151:696-702 [PMID: 19920270]
37. Lettieri CJ, Collen JF, Eliasson AH, Quast TN. Sedative Use During CPAP Titration Improves Subsequent Compliance. A Randomized, Double-Blinded, Placebo-Controlled Trial. Chest. 2009 136(5):1263-8 [PMID: 19567493]
38. Collen J, Lettieri C, Kelly W, Roop S. Clinical and polysomnographic predictors of short-term CPAP compliance. Chest. 2009; 135:704-709 [PMID: 19017888]
39. Kristo DA, Shah AA, Lettieri CJ, Macdermott SM, Andrada T, Taylor Y, Eliasson AH. Utility of split- night polysomnography in the diagnosis of upper airway resistance syndrome. Sleep Breath 2009;13:271-5 [PMID: 19052789]
40. Greenburg DL, Lettieri CJ, Eliasson AH. Effects of surgical weight loss on measures of obstructive sleep apnea: a meta-analysis. Am J Medicine 2009; 122:535-42 [PMID: 1942318]
41. Lettieri CJ, Shah A, Greenburg D. An intensivist-directed intensive care unit improves clinical outcomes in a combat zone. Crit Care Med. 2009; 37:1256-60 [PMID: 19242318]
42. Lettieri CJ, Eliasson AE. Pneumatic compression devices are an effective therapy for Restless Legs Syndrome: a prospective, randomized, double-blind, sham-controlled trial. Chest. 2009; 135:74-80 [PMID: 19017878]
43. Gambino S, King CS, Lettieri CJ. Multiple Pulmonary Carcinoid Tumorlets Mimicking Metastases in an Elderly Female With a History of Breast Cancer. Chest. 2009; 136:938-41 [PMID: 19736199]
44. Lettieri CJ, Eliasson AE, Greenburg D. Persistence of obstructive sleep apnea After Surgical Weight Loss. J Clin Sleep Med, 2008; 4:333-338 [PMID: 18763424]
45. Shah A, Lettieri CJ. Fulminant meningococcal sepsis in a woman with previously unknown hyposplenism. Medscape J Med. 2008; 10:36 [PMID: 18382706]
46. Lettieri CJ, Quast TN, Eliasson AH, Andrada T. Eszopiclone improves overnight polysomnography and continuous positive airway pressure titration: a prospective, randomized, placebo-controlled trial. Sleep 2008; 31:1310-1316 [PMID: 18788656]
47. Eliasson AE, Lettieri CJ. Sequential Compression Devices for Treatment of Restless Legs Syndrome.
Medicine 2007; 86:317-323 [PMID:18004176]
48. Shorr AF, Cors C, Lettieri CJ, Nathan SD. Pulmonary hypertension in patients with idiopathic pulmonary fibrosis awaiting lung transplantation. Eur Respir J. 2007; 30:715-21 [PMID: 17626111]
49. Salerno SM, Carlson DW, Soh EK, Lettieri CJ. Impact of perioperative cardiac assessment guidelines on management of orthopedic surgery patients. Am J Med. 2007; 120:185-6 [PMID: 17275461]
50. Lettieri C, Nathan S, Bennet S, Shorr A. Prevalence and Outcomes of Pulmonary Arterial Hypertension in Advanced Idiopathic Pulmonary Fibrosis. Chest 2006; 129:746-752 [PMID: 16537877]
51. Biega TJ, Lettieri CJ, Levy LM, Venbrux AC. Linear pulmonary opacities in an asymptomatic patient.
Respiration. 2006; 73:705-7 [PMID: 16636530]
52. Lettieri C, Nathan S, Browning R, Bennet S, Shorr A. Distance-Saturation Product as a Marker of Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis. Respir Med. 2006; 100:1734-41 [PMID: 16545950]
53. Moawad FJ, Hartzell JD, Biega TJ, Lettieri CJ. Transient blindness due to posterior reversible encephalopathy syndrome following ephedra overdose. South Med J. 2006; 99:511-4 [PMID: 16711314]
54. Lettieri C, Eliasson A, Andrada T, Khramtsov A, Raphaelson M, Kristo D. Obstructive Sleep Apnea Syndrome: Are We Missing an at-Risk Population. J Clin Sleep Med 2005; 1:381-385 [PMID: 17564406]
55. Lettieri C, Eliasson A, Andrada T, Kristo, D. Does Zolpidem Enhance the Yield of Polysomnography? J Clin Sleep Med 2005; 1:129-131 [PMID: 17561625]
56. Lettieri C, Veerappan G, Parker J, Hayden D, Travis W, Shorr A. Discordance Between General and Pulmonary Pathologists in Diagnosis of Interstitial Lung Disease. Respir Med. 2005; 99:1425-30 [PMID: 16210097]
57. Lettieri C, Veerappan G, Mulligan C, Shorr A. Outcomes and Safety of Surgical Lung Biopsy in Interstitial Lung Diseases. Chest. 2005; 127:1600-5 [PMID: 15888834]
58. Kristo D, Lettieri C, Andrada T, Khramtsov A, Eliasson A. Silent Upper Airway Resistance Syndrome: Prevalence in a Mixed Military Population. Chest. 2005; 127:1654-7 [PMID: 15888842]
59. Shorr AF, Helman DL, Lettieri CJ, Montilla JL, Bridwell RS. Depreotide Scanning In Sarcoidosis: A Pilot Study. Chest. 2004; 126:1337-43 [PMID: 154291183]
60. Lettieri C, Moon J, Hickey P, Berg B, Hospenthal D. Prevalence of Leptospira Antibodies in US Army Blood Bank Donors in Hawaii. Mil Med. 2004; 169:687-90 [PMID: 15495719]
61. Wilson R, Lettieri C, Fitzpatrick T, Shorr A. Intralobar Bronchopulmonary Sequestrations Associated with Bronchogenic Cysts. J Resp Dis. 2004; 123:201-204 [PMID: 15763459]
62. Arora R, Lettieri C. Claybaugh J. The effects of residency on physical fitness among military physicians.
Mil Med. 2004; 169:522-5 [PMID: 15291183]
63. Veerappan G, Lettieri C, Cuneo B. Squamous Cell Lung Cancer Presenting as a Malar Mass. Neoplasia, 2003;5 :467-468 [PMID: 14670184]
64. Lettieri C, Berg B. Clinical Features of Non-Hodgkin’s Lymphoma Presenting with Acute Liver Failure.
Am J Gastrenterol. 2003; 98:1641-1646 PMID: 12873593]
65. Lettieri C. Recurrent Pneumonia: A Diagnostic Puzzler. J Respir Dis 2003; 121:190
66. Veerappan G, Lettieri C. Bronchopulmonary Sequestration. J Postgrad Med. 2003; 49:280-281 [PMID: 14597798]
67. Lettieri C, Pina J, Goodpasture’s Syndrome; A Case of Delayed Appearance of Autoantibodies and Renal Disease. Mil Med. 2001; 166:827-30 [PMID: 11569450]
68. Howe EG, Lettieri CJ. Health Care Rationing in the Aged, Ethical and Clinical Perspectives. Drugs Aging. 1999; 15:37-47 [PMID: 10459731]
PUBLICATIONS: EDITORIALS
1. Williams SG, Collen JF, Lettieri CJ. More Than Just a Good Night's Sleep: Commentary on "Lack of Resilience is Related to Stress-Related Sleep Reactivity, Hyperarousal and Emotion Dysregulation in Insomnia Disorder. J Clin Sleep Med 2018; 14(5):709-710. [PMID: 29734999]
2. Collen JF, Williams SG, Lettieri CJ. Doomed to Repeat History: The Burden of Trauma-Related Nightmares in Military Personnel. J Clin Sleep Med. 2018; 14(3):303-305 [PMID: 29458710]
3. Eliasson AH, Lettieri CJ, Netzer N. Sleep Medicine is coming of age in military medicine. Report from the Military Health System Research Symposium (2017). Sleep Breath 2017; 22(2):481-483 [PMID: 29151231]
4. Williams SJ, Collen JF, Lettieri CJ. The Continued Search for Optimal Therapy in Patients with OSA and PTSD. J Clin Sleep Med. May 2017; 13:849 [PMID: 28502285]
5. Lettieri CJ, Collen JF, Williams SJ. Challenges in the Management of OSA and PTSD. Is the Low Arousal Threshold an Unrealized Target? J Clin Sleep Med. 2017; 13:845-846 [PMID: 28416046]
6. Lettieri CJ, Williams SJ. The PTSD-OSA paradox: They are commonly associated and they worsen outcomes, but treatment non-adherence is common and the therapeutic effect limited. What are clinicians to do? J Clin Sleep Med. 2017; 13(1):5-6 [PMID: 27998382]
7. Lettieri CJ, Walter RJ. The Effects of Group Education on Continuous Positive Airway Pressure Adherence: Could it be more efficient as well as more effective? J Clin Sleep Med 2013; 9:975-6 [PMID: 23997713]
8. Collen J, Lettieri C, Hoffman M. The Impact of Post-Traumatic Stress Disorder on CPAP Adherence in Patients with Obstructive Sleep Apnea. J Clin Sleep Med. 2013; 9:1-2 [PMID: 23381338]
9. Holley AB, Lettieri CJ. Sleep Disruptions in the Intensive Care Unit: Effect on Outcomes. MedScape Forums, 2010
10. Walter RJ, Lettieri CJ. Safety of Long Acting beta Agonists. MedScape Forums, 2010
11. Shorr AF, Lettieri CJ, Helman DL. Role for transbronchial biopsy in the diagnosis of usual interstitial pneumonia. Chest. 2007; 131:329-30 [PMID: 17218598]
12. Eliasson AH, Lettieri CJ. Measuring nuclear factor-KB--who cares? Sleep Breath. 2006; 10:4-5 [PMID:16421763]
PUBLICATIONS: BOOK CHAPTERS
1. Lettieri CJ, Williams SJ. REM Sleep Parasomnias in Clinical Decision Support: Sleep Medicine. Ed. Pien, Wang. 2017 (2nd edition). Decision Support in Medicine, LLC. Wilmington, DE
2. Lettieri CJ, Williams SJ. Treatment of Sleep Disorders in PTSD. Sleep and Combat Related PTSD. Ed. Vermetten E. Springer. 2016
3. Lettieri CJ, Almeida F, Cistulli P, Clotilde M. Oral Appliances for Sleep Disordered Breathing and Sleep Bruxism. Principles and Practices of Sleep Medicine. 6th Edition. Ed Kryger. 2014
4. Lettieri CJ, Eliasson AE. Pneumatic compression devices are an effective therapy for Restless Legs Syndrome: a prospective, randomized, double-blind, sham-controlled trial. Best of Sleep Medicine, 2009
5. Lettieri CJ, Collen JF, Eliasson AH, Quast TN. Sedative Use During CPAP Titration Improves Subsequent Compliance. A Randomized, Double-Blinded, Placebo-Controlled Trial. Best of Sleep Medicine, 2009
6. Collen J, Lettieri C, Kelly W, Roop S. Clinical predictors of short-term CPAP compliance. Best of Sleep Medicine, 2009
7. Lettieri CJ. Multiple sections. Pulmonary Medicine (Pleural Diseases, Pneumonia, ARDS, Pulmonary Embolism, Apnea, COPD, Asthma, Dyspnea, Thoracentesis, Cough, Pulse Oximetry). In: Special Operations Forces Medical Handbook, Second Edition. Jackson, Wyoming: Teton NewMedia; 2008
8. Nolte R, Lettieri CJ. Exercise Induced Asthma. The Sports Medicine Resource Manual, ed. Seidenberg PH. Elsevier publishing. 2007
9. Nguyen D, Lettieri CJ. Cardiovascular Consequences of Obstructive Sleep Apnea Syndrome. US Respiratory Diseases, Touch Publishing, Issue II, 2006
10. Lettieri CJ, Mikita JM. Obstructive Sleep Apnea Syndrome. US Respiratory Diseases, Touch Publishing, Issue I, 2006
11. Mikita JA, Lettieri CJ, Parker JM. Causes of Dyspnea in the Military Recruit. Textbook of Military Medicine: Recruit Medicine. Ed Dekopning BL, Lenhart MK, Lounsbury DL. 2006
PUBLICATIONS: PUBLISHED ABSTRACTS
1. Warren WA, Walter RJ, Switzer MS, Lettieri CJ. Correlation Between Positive Airway Pressure and Medication Adherence - the Healthy User Effect. Sleep 2016; 39; A277
2. Hudson A, Walter R, Flynn J, Capaldi V, Rodgers M, Lettieri C. No Change in Home Sleep Testing Parameters in Ambulatory Orthopedic Surgical patients with and without OSA, A Prospective Observational Study. Sleep 2016; 39; A271
3. Smith P, Lettieri CJ, Sheikh K. Treatment adherence in Atrial Fibrillation patients diagnosed with OSA after direct referral for polysomnography. Sleep 2016; 39; A161
4. Daniels R, Sheikh K, Andrada T, Howard R, Collen J, Lettieri C, Eliasson A. Is the Epworth sleepiness scale useful for predicting OSA? Sleep 2016; 39:A129
5. Walter RJ, Lettieri CJ, Sheikh K, Rodgers M, Capaldi VF. Does Medication Adherence Predict CPAP Compliance? Sleep 2015; 36: A200
6. Lettieri CJ, Collen JC, Williams SG. Comorbid OSA and PTSD: Effect of outcomes and impact of CPAP therapy. Sleep 2014; 37:A107
7. Collen J, Lettieri CJ. Early CPAP use impacts long-term weight loss in bariatric surgery patients. Sleep 2013; 36:A177
8. Williams SG, Holley AH, Lesage S, Lettieri C. Respiratory Inductance Plethysmography compared with Thermister and Pressure Airflow Transduction to Identify Obstructive Sleep Disordered Breathing, Sleep, 2012; 35:A3095
9. Dombrowksy J, Lettieri C, McCarthy JG, Shah A, Holley A. The prevalence of erectile dysfunction and impact of CPAP therapy: A prospective analysis. Sleep, 2012; 35:A0574
10. Collen J, Orr N, Carter K, Holley A, Lettieri C. Sleep Disorders in Operation Iraqi Freedom and Operation Enduring Freedom Veterans Chest 2011; 140:4 970A
11. Collen J, Hoffman M, Lettieri C. The Impact of Posttraumatic Stress Disorder on Continuous Positive Airway Pressure Adherence in Patients With Comorbid OSA Chest 2011; 140:4 1073A
12. Collen JF, Orr N, Holley A, Lettieri C. Sleep disorders in combat related traumatic brain injury. Am J Resp Crit Care Med, 2011 pA5254
13. Lettieri CF, Lettieri CJ, Carter KA. Does Home Sleep Testing Impair CPAP Adherence in Patients With Obstructive Sleep Apnea? Chest 2010; 138:888A
14. Orr N, Carter KA, Collen JF, Hoffman M, Holley AB, Lettieri CJ. Prevalence of Sleep Disorders Among Soldiers With Combat-Related Posttraumatic Stress Disorder. Chest 2010; 138:704A
15. Walter RJ, Hagedorn S, Lettieri CJ. Management of Obstructive Sleep Apnea and Its Effect on Health- care Resource Utilization. Chest 2010; 138:783A
16. Walter RJ, Shah AA, Lettieri CJ. The Effects of Individual vs Group Education on Continuous Positive Airway Pressure Compliance in Patients with Obstructive Sleep Apnea. Chest 2010; 138:889A
17. Greer J, Holley AB, Barnes S, Lukes Y, Morris E, Collen JF, Lettieri CJ. Gene Methylation in Bronchoalveolar Lavage Fluid From Patients With Cancer, Inflammatory Lung Disease, and Tobacco Exposure. Chest 2010; 138:244A
18. Hoffman M, Lettieri C. Adherence to continuous positive airway pressure treatment of Obstructive Sleep Apnea in patients with post traumatic stress disorder. Sleep. 2010; 33:A237
19. Carter KA, Lettieri CJ. Traumatic Brain Injury induced Hypersomnia Following Repetitive Blast Injuries in Iraq. Sleep. 2010; 33:A267
20. Carter KA, Lettieri CJ. Lettieri CF, Hoffman M, Nassar P. Does Home Sleep Testing Impair CPAP compliance in Patients with Obstructive Sleep Apnea? Sleep. 2010; 33:A172
21. Greer J, Holley AB, Collen J, Shah AA, Lettieri CJ. Gene Methylation in Bronchoalveolar Lavage Fluid from Patients with Cancer, Inflammatory Lung Disease, and Tobacco Exposure. Am J Respir Crit Care Med. 2010, 181; 2010:A209
22. Hagedorn SI, Walter RJ, Lettieri CJ. Impact of Positive Airway Pressure on Health Care Utilization in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2010, 181; 2010:A5564
23. Shah AA, Lettieri CJ, Holley AB, Kelly WF, Roop SA. Continuous Positive Airway pressure Adherence Correlates with Improved Quality of Life. Chest 2009 136: 24S-f
24. Shah AA, Lettieri CJ, Holley AB, Mikita JA. The efficacy of oral appliances in Obstructive Sleep Apnea. Chest 2009 136: 43S-e
25. Collen JF, Lettieri CJ, Eliasson AE, Quast T. Sedative use during CPAP titration improves subsequent compliance: A prospective, randomized, double-blinded, placebo controlled trial. Chest 2009 136: 23S-e
26. Magee CD, Shah AA, Lettieri CJ. Bronchial artery embolization for massive hemoptysis in cavitary sarcoidosis. Chest 2009 136: 64S-c
27. Shah AA, Lettieri CJ, Holley AB, Roop SR, Kelly WF. Eszopiclone Improves Continuous Positive Airway Pressure Compliance: A Prospective, Randomized, Placebo-Controlled Trial. Am J Respir Crit Care Med 179;2009:A1262
28. Shah AA, Lettieri CJ, Holley AB, Roop SR, Kelly WF. Eszopiclone Improves Short and Intermediate term CPAP Compliance. Sleep, 2009;32S:A184
29. Holley AB, Shah AA, Roop SR, Kelly WF, Lettieri CJ. A Prospective Evaluation of Treatment Outcomes in Mild OSAS. Sleep, 2009;32S:A232
30. Collen JF, Holley AB, Lettieri C, Shah AA, Kelly W, Roop S. The impact of split-night versus traditional sleep studies on CPAP compliance. Am J Respir Crit Care Med 2009; 179:A1259.
31. Collen JF, Holley AB, Lettieri C, Shah AA, Kelly W, Roop S. The impact of split-night versus traditional sleep studies on CPAP compliance. Sleep, 2009; 32S:A181
32. Andrada T, Lettieri C, Khramtsov A, Holley A, Roop S, Patterson H Accuracy of Pressure Transducer Airflow for the Diagnosis of Upper Airway resistance Syndrome. Sleep 2009;32S:A385
33. Eliasson AH, Kashani M, Lettieri C, Vernalis M. Correlations between activity and sleep. Sleep 2009;32S:A417
34. King CS, Gambino S, Lettieri C. Multiple Pulmonary Carcinoid Tumorlets Mimicking Metastates in an Elderly Female With a History of Breast Cancer. Chest 2008; 134:37003S.
35. Shah AA, Lettieri CJ, Kristo DA, MacDermott SM, Andrada T, Taylor Y, Eliasson AH. Split-night Polysomnography in Upper Airway Resistance Syndrome. Chest 2008 134: s52003
36. Woodrow JP, Lettieri CJ, Greenburg DL. Changes in Six Minute Walk Test Measurements Over Time as a Predictor of Mortality in Idiopathic Pulmonary Fibrosis. Chest 2008; 134: s20001
37. Collen JF, Lettieri CJ, Kelly W, Roop SA. Clinical and Polysomnographic Predictors of Short-term CPAP Compliance. Chest. 2008; 134:s60003
38. Lettieri CJ, Quast TN, Eliasson AH Eszopiclone Improves The Quality Of Polysomnography: A Prospective, Randomized, Placebo-Controlled Trial. Sleep 2008; 31:A201
39. Lettieri CJ, Eliasson AH, Greenburg DL. Weight Loss After Bariatric Surgery Improves, But Does Not Resolve Obstructive Sleep Apnea. Sleep 2008; 31:A201
40. Eliasson AH, Lettieri C, Eliasson A. Sleep And Academic Performance In A Community College. Sleep 2008; 31:A127
41. Shah A, Lettieri CJ, Greenburg DL. Intensivist-Model ICU Improves Clinical Outcomes in a Combat Zone. Am J Respir Crit Care Med 2008; 117:A988
42. Quast TM, Lettieri CJ, Eliasson AH. Eszopiclone improves overnight polysomnography and continuous positive airway pressure titration: a prospective, randomized, placebo-controlled trial. Am J Respir Crit Care Med 2008; 177:A804
43. Shorr AF, Wainwright J, Lettieri CJ, Helman D. The impact of pulmonary hypertension on survival in patients with idiopathic pulmonary fibrosis listed for lung transplant. Chest 2007; 132:428S
44. Mikita, JA, Lettieri CJ, George SA, Mahakian CG, Koudelka BM, Eliasson AH. Oral Appliance Overtitration in Obstructive Sleep Apnea. Am J Respir Crit Care Med 2006; 115:A869
45. Holley AB, Lettieri CJ, Eliasson AH. Positional Therapy and CPAP Compliance in Patients Diagnosed with OSA. Am J Respir Crit Care Med 2006; 115:A871
46. George SA, Mikita, JA, Lettieri CJ, Mahakian CG, Koudelka BM, Eliasson AH. Oral Appliance Overtitration in Obstructive Sleep Apnea. Am J Respir Crit Care Med 2006; 115:A871
47. MacDermott SM, Kristo DA, Lettieri CJ, Andrada T, Taylor Y, Eliasson AH. Split Night Polysomnography In The Diagnosis And Treatment Of The Upper Airway Resistance Syndrome. Sleep2006; 29:A179
48. Lettieri CJ, Eliasson AH, Andrada T, Khramtsov A, Kristo DA. Does Zolpidem Enhance The Yield Of Polysomnography? Sleep 2005; 28:A319
49. Shorr AF, Cors C, Lettieri CJ, Nathan SD. Severe Pulmonary Hypertension in Idiopathic Pulmonary Fibrosis. American College of Chest Physicians meeting. Chest 2006; 130:151
50. Lettieri C, Eliasson A, Andrada T, Khramtsov A, Raphaelson M, Kristo D. Obstructive Sleep Apnea Syndrome: are we missing an at-risk population? Chest 2005;128:133S
51. Lettieri C, Nathan S, Bennet S, Shorr A. Incidence and Outcomes of Pulmonary Arterial Hypertension in Idiopathic Pulmonary Fibrosis. Chest 2005;128:217-218S
52. Shorr AF, Cors C, Lettieri CJ, Nathan SD. Intermediate-term Outcome Following Transplantation for Sarcoidosis and Idiopathic Pulmonary Fibrosis. Chest 2005;128:203-204S
53. Shorr AF, Lettieri CJ, Davies DB, Nathan SD. Two-year Outcomes for Patients with Sarcoidosis Following Lung Transplantation. Chest 2005;128:210S
54. Shorr AF, Cors CS, Helman DL, Lettieri CJ, Nathan SD. Pulmonary Hypertension in Idiopathic Pulmonary Fibrosis: Epidemiology and Potential Risk Factors. Chest 2005;128:218S
55. Lettieri C, Eliasson A, Andrada T, Kristo, D. Does Zolpidem Enhance the Yield of Polysomnography. Sleep 2005;28S:A318
56. Lettieri C, Nathan S, Interferon Gamma 1-b Improves Exercise Tolerance in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med 2005;A123
57. Shorr AF, Davies DB, Helman DL, Lettieri CJ, Nathan SD. Pulmonary Hypertension in Sarcoidosis: Insights as to Mechanisms. Am J Respir Crit Care Med 2005;A128
58. Lettieri C, Nathan S, Browning R, Bennet S, Shorr A. Distance-Saturation Product as a Marker of Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis. Chest 2004;126:888-9S
59. Burton NB, Browning RF, Lettieri CJ, Valentine VG, Ahmad S, Nathan SD. Outcomes of Lung Transplantation in Patients with IPF Receiving Gamma-Interferon 1b. Chest 2004;126:889S
60. Shorr AF, Davies BD, Helman DL, Lettieri CJ, Nathan SD. Pulmonary Hypertension in Sarcoidosis: Identifying Potential Risk Factors. Chest 2004 126:742S-b-743S-b
61. Lettieri C, Veerappan G, Parker J, Hayden D, Travis W, Shorr A. Poor Agreement Between General and Pulmonary Pathologists in the Diagnosis of Interstitial Lung Disease. Am J Respir Crit Care Med 2004;A232
62. Lettieri C, Veerappan G, Helman D, Mulligan C, Shorr A. Safety of Surgical Lung Biopsy in Suspected Idiopathic Pulmonary Fibrosis. Chest. 2003;124:116S
63. Lettieri C. Intralobar Bronchopulmonary Sequestrations Associated with Bronchogenic Cysts. Chest. 2003;124:305-306S
64. Shorr A, Lettieri C, Montila J, Bridwell R. Depreotide Scanning in Sarcoidosis: A Pilot Study. Chest. 2003;124:108-109S
65. Hospenthal DR, Lettieri CJ, Moon JE, Hickey PW, Gray MR, Berg BW. Prevalence of Leptospiral antibody in US Army blood donors in Hawaii. Am J Trop Med Hyg 2002;67S:192
66. Lettieri CJ, Fandre M, Baroni DS. Lymphoma presenting as fulminant hepatic failure; a case report and review of the literature. American Journal of Gastroenterology. 2000;95:2516-2517
67. Griesemer D, Talwar D, Lettieri C. Impaired Language Development Resulting from Temporal Lobe Epileptiform Foci. Epilespsia 1994;212:118S
RESEARCH PROTOCOLS
2017 – 2019 Associate Investigator, WRNMMC DCI # pending
“Whole genome sequencing in sleep disorders and Posttraumatic Stress Disorder (PTSD) in a Military Healthcare System population”
2017 – 2020 Associate Investigator, “Identifying Predictors of Treatment Response in Service members with Posttraumatic Stress Disorder-Related Sleep Disturbances: Use of Large Datasets to Improve Treatment Selection over the Military Lifecycle.
Grant Award: Defense Health Agency Joint Program Committee 5 (JPC-5) - $2,167,000
2015 – 2018 Associate Investigator, Univ Chicago Protocol # PR151832
“Impact of OSA Treatment of Cardiometabolic Profile in Prediabetes and Type II Diabetes: The Role of REM Sleep”
2014 – 2016 Associate Investigator, WRNMMC DCI # 405089-6.
“Online cognitive-behavioral treatment for insomnia (OCBT-I) in the primary care setting: An efficacy and feasibility study.”
Grant Award: US Army. $350,000
2014 – 2016 Associate Investigator, WRNMMC DCI #393668-1
“I-TRACH criteria and the predictive value of prolonged mechanical ventilation”
2013 – 2015 Associate Investigator, WRNMMC DCI # 388140-1. ClinicalTrials: NCT01861652
“The Use of the Vasculaire Leg Compression Device for the treatment of Restless Leg Syndrome in Patients Who Have Failed Medical Therapy- A Prospective Clinical Study.
Grant Award: Vasculair, Inc. $45,000
2013 – 2015 Associate Investigator, USU cite #CNRM-75-2445.
“The Impact of Growth Hormone Releasing Hormone on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Developed Insomnia.”
Grant Award: Center for Neuroscience and Regenerative Medicine, $464,080 HJF#306136-7.01-06855
2013 – 2015 Associate Investigator, WRNMMC DCI # 397209-1. ClinicalTrials: NCT01851798 “Postoperative management strategies for hip and knee arthroplasty surgical patients diagnosed with or at risk for obstructive sleep apnea: a prospective randomized controlled pilot study.” Grant Award: USUHS, $5,000
2012 – 2014 Associate Investigator, WRNMMC DCI # 384867-1. ClinicalTrials: NCT01851798 “Postoperative Home Sleep Test changes in ambulatory surgical patients with and without obstructive sleep apnea: a prospective clinical study.”
Grant Award: USUHS, $5,000
2012 – 2013 Associate Investigator, BAMC DCI #375176-1.
“Relationship between periodic breathing during sleep and cognitive performance following acute ascent to high altitude in military personnel”
2011 – 2013 Associate Investigator, WRNMMC DCI # 370925-3.
“Accuracy of Calibrated Respiratory Inductance Plethysmography in Identifying Obstructive Respiratory Events.”
2011 – 2012 Associate Investigator, WRAMC DCI # 364857
“Are physicians adherent with the NAEPP Guidelines for the diagnosis and treatment of Asthma?”
2011 – 2012 Associate Investigator, WRAMC DCI # 364496
“Predictors of mechanical ventilator duration and need for early tracheostomy”
2011 – 2012 Associate Investigator, WRAMC DCI # 359862
“The Effects of Individual versus Group Education on Continuous Positive Airway Pressure Compliance in Patients with OSA.”
2010 – 2011 Associate Investigator, WRAMC DCI # 355213-1
“Sleep disturbances in soldiers with traumatic brain injury and/or posttraumatic stress disorder”
2010 – 2011 Associate Investigator, WRAMC DCI #354714-1
“Prospective, Randomized Trial Assessing the mCare System on CPAP Adherence.” Grant Award: US Army TATRC, $165,000
2010 – 2011 Associate Investigator, WRAMC DCI #350570-1 “PTSD and CPAP compliance”
2009 – 2010 Associate Investigator, WRAMC DCI # 359862-2
“Impact of PAP Treatment on Health Care Utilization in Patients with OSA.”
2009 – 2010 Associate Investigator, WRAMC DCI #10-7285EX-351946-1
“Does Home Sleep testing Impair CPAP Compliance in Patients with OSA?”
2009 – 2010 Associate Investigator, WRAMC DCI #05-17048EX
“The utility of oral appliances in the treatment of obstructive sleep apnea.” Grant Award: US Army TATRC, contract #: W81XWH-10-2-0020, $90,000
2009 – 2010 Associate Investigator, WRAMC DCI # 20085-1
“Does pretreatment with eszopiclone prior to CPAP titration improve short-term compliance”
2009 – 2010 Associate Investigator, WRAMC DCI # 09-7109
“Fluid Analysis for Hypermethylated DNA in Patient with Lung Cancer”
2008 – 2010 Associate Investigator, WRAMC DCI #08-06879
“Clinical and Polysomnographic Predictors of CPAP Compliance”
2008 – 2010 Associate Investigator, WRAMC DCI #08-06834
“Serial Six-Minute walk testing as a predictor of mortality in Idiopathic Pulmonary Fibrosis.”
2007 – 2009 Primary Investigator, WRAMC DCI #07-17022 Clinical Trials Registry: NCT00612157
“Prospective Randomized Placebo Controlled Trial Using Non-benzodiazepine hypnotics to Improve CPAP Compliance.”
Grant Award: Sepracor, $149,420 [ESRC-966]
2006 – 2008 Primary Investigator, WRAMC DCI #05-17018, Clinical Trials Registry: NCT00479531. “Sequential Compression Devices for Treatment of Restless Legs Syndrome - Prospective, Randomized, Sham-Controlled Study. “
Grant Award: Aircast, $27,800 [MA-019]
2006 – 2008 Primary Investigator, WRAMC DCI #05-17017, Clinical Trials Registry: NCT00507117 “Prospective Randomized Placebo Controlled Trial Using Eszopiclone to Improve the Quality of Polysomnography”
Grant Award: Sepracor, $78,762 [ESRC-088]
2006 – 2008 Primary Investigator, WRAMC DCI #05-17009
“Sequential Compression Devices for Treatment of Restless Legs Syndrome - a Prospective, Randomized, Sham-Controlled Study Work Unit”
2005 – 2007 Primary Investigator, WRAMC DCI #05-17047EX
“Doses the use of CPAP/BiPAP decrease wound dehiscence rate after bariatric surgery”
2004 – 2005 Primary Investigator, WRAMC DCI #05-170044EX
Respiratory Inductive Plethysmography for the Diagnosis of Upper Airway Resistance Syndrome.”
2004 – 2005 Primary Investigator, WRAMC DCI #05-17043EX “Silent Upper Airway Resistance.”
2004 – 2005 Primary Investigator, WRAMC DCI #05-17045EX
“Does Zolpidem Enhance the Yield of Polysomnography”
2002 – 2003 Primary Investigator, WRAMC DCI #03-17021EX
“Predictors of Outcomes for Surgical Lung Biopsies in Patient with Interstitial Lung Disease”
2002 – 2003 Primary Investigator, WRAMC DCI #03-17015
“Tc-99m Depreotide Scanning in Idiopathic Pulmonary Fibrosis.” Grant Award: US Army, $5,000
2001 – 2004 Associate Investigator, TAMC DCI #42H02
“Utility of the AAC-AHA Guidelines to Predict Perioperative Cardiac Events.”
2001 – 2002 Associate Investigator, TAMC DCI protocol #35H02
“Effects of Residency on Physical Fitness Among Military Physicians.”
2001 – 2004 Associate Investigator, TAMC DCI protocol #51H01
“Seroepidemiology of Bartonella henselae in US Army Blood Bank Donors in Hawaii.”
1999 – 2002 Primary Investigator, TAMC DCI protocol #42H00
“Seroepidemiology of Leptospirosis in US Army Blood Bank Donors in Hawaii.”
GRAND ROUNDS AND INVITED LECTURES (CME EVENTS)
Oral appliances vs. PAP. Virginia Academy of Sleep Medicine. Nov 2018
The Association Between OSA and PTSD. Virginia Academy of Sleep Medicine. Nov 2018
Managing Sleep in Inpatients. Academy of Consult Liaison Psychiatry. Orlando, Nov. 2018
Mild OSA: To Treat, or Not To Treat. American College of Chest Physicians, Oct 2018
Managing Veterans with OSA and PTSD. American College of Chest Physicians, Oct 2018
CPAP Made Simple - How to Optimize Comfort and Outcomes. Sleep for Life, Sep 2018
OSA and PTSD: Understanding the Association and Impact on Outcomes. Canadian Sleep Disorders Disciplines. Nov 2017
Sleep Disorders Among Inpatients. Academy of Psychosomatic Medicine. Nov 2017
The Association Between OSA and Atrial Fibrillation. American Academy of Cardiovascular Sleep Medicine, Oct 2017
Comparative Efficacy of Oral appliances and CPAP: Univ of the Pacific School of Dentistry. September 2017
The value of an inter-disciplinary team approach in the management of sleep disorders. Case Management Society of America. June 2017
The Role of Oral Appliances in the Treatment of OSA and Comorbid PTSD. American Academy of Dental Sleep Medicine, June 2017
Value-Based Medicine: Sleep Medicine Across the Spectrum of Military Operations. American Academy of Sleep Medicine, June 2017
Oral appliances and CPAP: Individualizing therapy to optimize care. Univ of the Pacific School of Dentistry. September 2016
PTSD and Sleep Disorders Sleep Disorders and Chronic Care 2016. Sep 2016
Is OSA Really a Risk Factor for CVA and Does Treatment Improve Outcomes? American Academy of Cardiovascular Sleep Medicine, June 2016
OA vs CPAP vs APAP vs BIPAP vs VPAP: What is the Most Efficacious Treatment for OSA? American Academy of Dental Sleep Medicine, June 2016
Understanding the Rules and Regulations Regarding Oral Appliance Use in Pilots and Commercial Drivers. American Academy of Dental Sleep Medicine, June 2016
Sleep and Performance, Grand Rounds, Providence Hospital, May 2016
Updates in Pulmonary Medicine, American College of Physicians, VA Chapter Meeting, Mar 2016
Lung Cancer Screening, American College of Physicians, VA Chapter Meeting, Mar 2016
PTSD and OSA; Optimizing Outcomes. American College of Chest Physicians, Montreal, Oct 2015
Understanding the Link Between Sleep and Pain, 2015 Pain Medicine Summit, September 2015
Should All Patients with Atrial Fibrillation Proceed Directly to the Sleep Lab? American Academy of Cardiovascular Sleep Medicine, Keynote Speaker, June 2015
Comparative Effectiveness of OA Therapy Versus CPAP on Health Outcomes and Mortality in OSA, American Professional Sleep Societies Annual Meeting, June 2015
Sleep, Pain, and Depression. Maryland Sleep Society Annual Meeting, April 2014
Depression, Pain, TBI, PTSD and Sleep. Univ of Maryland VA Resiliency Course, March 2014
Sleep Disorders with TBI and PTSD. Virginia Academy of Sleep Medicine, November 2013
Sleep and Psychiatric Disorders. Psychiatry Updates. Uniformed Service University, September 2013
Home Sleep Testing in the evaluation of OSA. University of Maryland, July 2013
Sleep Issues in the Military Population. Kenneth L. Artiss Symposium, June 2013
A Systematic Approach to Challenging PAP Adherence. APSS Post Graduate Seminar, June 2013
Sleep, Sleep Debt and GME. Keynote address, National Capital Consortium, Mar 2013
Improving CPAP Adherence. University of Utah Medical Center, Jan 2013
Using Oral Appliances in OSA. American Academy of Otolaryngology Annual Meeting, Sep 2012
OSA in Dental Medicine. American Academy of Dental Sleep Medicine, June 2012
Using technology to enhance CPAP Adherence. George Washington University Hospital, May 2012
Latent Tuberculosis Infections. Rader Medical Clinic, Grand Rounds. December 2011
OSA; A 2011-12 Update. Sleep in the Community Workshop. December 2011
Home Sleep Testing, Best Practices, AASM Workshop, October 2011
Updates on Portable Monitors, AASM Workshop, October 2011
When CPAP Fails, AASM Workshop, October 2011
Technologic Advancements and CPAP Adherence, AASM Workshop, October 2011
Circadian Rhythm Disorders, George Washington University, April 2011
Circadian Rhythm Disorders, Maryland Sleep Medicine Workshop, September 2010
Common Sleep Disorders in Primary Care, USAFP Conference, New Orleans, February 2010
Sleep Deprivation and Shift Worker. Malcolm Grow Medical Center, December 2009
Shift Work Sleep Disorder. University of Georgia, October 2009
Shift Work Sleep Disorder. DeWitt Army Community Hospital, October 2009
Restless Legs Syndrome. Virginia Academy of Sleep Medicine, Key Note Speaker, September 2009
Hypersomnia and the Primary Care Provider. Dwight D Eisenhower Medical Center, August 2009
The Effects of Sleep Deprivation. University of Maryland Medical Center, August 2009
Diagnosis and Management of COPD: Maryland General Hospital, May 2009
Home Sleep Testing in Sleep Disordered Breathing: DeWitt Army Community Hospital, May 2009
Diagnosis and Management of COPD: Kimbrough Clinic Grand Rounds Series, May 2009
Moving Your ICU During a Disaster. American College of Chest Physicians, October 2008
Obstructive Sleep Apnea: Capital Conference Family Medicine Board Review, June 2008
Treatment of Sleep Disordered Breathing: Malcom Grow Medical Center, June 2008
Updates on COPD: DeWitt Army Community Hospital, April 2008
Psychiatric Consequences of Sleep Disorders. Portsmouth Naval Hospital, November 2007
Establishing an ICU disaster response plan. American College of Chest Physicians, November 2007
New Guidelines in the Diagnosis and Treatment of Asthma: Walter Reed Medical Center, Oct 2007
Disaster Preparedness and Mitigation. American Thoracic Society, Post Graduate Course, May 2007
Emerging infectious diseases and natural disasters. American Thoracic Society, May 2007
Pulmonary Mycobacterial Infections: Worldwide Teleconference, November 2006
Diagnosis and Treatment of Tuberculosis. Capital Conference Family Med Board Review, June 2006
Gaps in disaster preparedness. American Thoracic Society Scientific Symposium, May 2006
An overview of disaster medicine. American Thoracic Society, Post Graduate Course, May 2006
Airway Management and Use of Paralytics. Walter Reed Army Medical Center, February 2006
Sleep-Disordered Breathing, DeWitt Army Community Hospital. April 2005
Sleep Disorders for the Primary Care Provider. DeWitt Army Community Hospital. Feb 2005
Fulminant Hepatic Failure. Dept of Medicine, Walter Reed Army Medical Center. May 2004
Updates in the Management of Asthma and COPD. DeWitt Army Community Hospital. Mar 2004