Edward J. Septimus
Education
1968
B.S. Biological Sciences, Ohio State University
1972
M.D., Medicine, Baylor College of Medicine
Postdoctoral Training
1972-1975
Resident in Medicine, Baylor Affiliated Hospitals
1975-1977
Fellow in Infectious Diseases, Baylor Affiliated Hospitals
Faculty Academic Appointments
1977-2002
Assistant Clinical Professor of Medicine, Baylor College of Medicine
1978-1981
Assistant Clinical Professor of Medicine, Program in Infectious Diseases and Clinical Microbiology, University of Texas Health Science Center-Houston
1981-1991
Associate Clinical Professor of Medicine, Program in Infectious Diseases and Clinical Microbiology, University of Texas Health Science Center-Houston
1988-2004
Associate Clinical Professor Family Practice and Community, Medicine University of Texas Health Science Center-Houston
1991-2008
Clinical Professor Internal Medicine and Infectious Diseases, University of Texas Health Science Center-Houston
2002-2006
Associate Clinical Professor of Medicine, Baylor College of Medicine
2009-present
Affiliate Professor, Distinguished Senior Fellow, School of Public Health, George Mason University
2009-present
Clinical Professor Internal Medicine, Texas A&M College of Medicine, Houston
2018-present
Senior Lecturer, Department of Population Medicine, Harvard Medical School
Appointments at Hospitals
1976-1977
Provisional Medical Staff Internal Medicine, Memorial Hermann Southwest
1977-2005
Active Medical Staff Internal Medicine, Memorial Hermann Southwest
2005-2007
Active Staff Internal Medicine, Billings Clinic
2008-2009
Provisional Medical Staff Internal Medicine, Memorial Hermann Southwest
Major Administrative Leadership Positions
Local/Regional
1978-1996
Program Director, Internal Medicine, Memorial Hermann Southwest
1978-2005
Chief Infectious Diseases, Memorial Hermann Southwest
1982-1998
Director, Infectious Diseases, Memorial Healthcare System
1986-1998
Medical Director, Occupational Health Services, Memorial Healthcare System
1989-1991
Chair, Medical Advisory Council, Greater Houston AIDS Alliance
1992-1994
Expert Review Panel, Texas State Board of Dental Examiners
1992-1995
Faculty Senate, University of Texas Health Science Center-Houston
1994-1995
President Texas Infectious Diseases Society
1998-2005
Medical Director Infectious Diseases, Occupational Health, and Pharmacy Memorial Hermann Healthcare System
2001-2005
Medical Advisory Steering Committee Houston Task Force on Terrorism
2006-2007
Medical Director Infectious Diseases and Patient Safety, Billings Clinic
2008-2016
Medical Director Infection Prevention and Epidemiology, Clinical Services Group HCA Healthcare
2010-2011
President Texas Infectious Diseases Society
2016-2018
VP Research and Infectious Diseases, Clinical Services Group HCA Healthcare
2016-present
Steering Committee Gulf Coast Consortia Cluster for Antimicrobial Resistance
National
1996-1998
Chair, State and Regional Societies, Infectious Diseases Society of America (IDSA)
2006-2009
Board of Directors, IDSA
2010-present
Chair, Scientific Advisory Committee Center for the Study of International Medical Policies and Practices
2012-2013
Co-chair Infectious Disease Endorsement Maintenance Committee, National Quality Forum (NQF)
2014-present
Co-chair Patient Safety Committee, NQF
2015-2016
Co-chair Antibiotic Stewardship in Acute Care: A Practical Approach, NQF
2017-
MAD-ID Scientific Committee
2017-
Editorial Advisory Board Contagion
2018-
Chair Healthcare Safety Advisory Committee, Texas Department of State Health Services
Committee Service
Local/Regional
1978-2005
Infection Control Committee, Memorial Hermann Southwest
1983-2003
Pharmacy and Therapeutics Committee, Memorial Hermann Southwest
2003-2005
Quality Board, Memorial Hermann Healthcare System
2011-2016
Healthcare-Associated Infections and Preventable Adverse Events Advisory Panel, Texas Department of State Health Services
2017-present
Healthcare Safety Advisory Committee, Texas Department of State Health Services
National/International
1984-1985
Educational Activities Committee, Society of Hospital Epidemiologists of America (SHEA)
1984-1986
Standards Committee, Association for Practitioners in Infection Control (APIC)
1985-1990
Clinical Affairs Committee, IDSA
1991-1992
Guidelines Committee, International Association for Health Care Central Service, Material Managers
1995-1998
Board, State and Regional Societies, IDSA
1996-2000
Program Committee, IDSA
2004-2008
Delegate to the American Medical Association, IDSA
2004-2016
Quality Measures Committee, IDSA
2005-2016
Antimicrobial Resistance Committee, IDSA
2008-
Anti-Infective Drugs Advisory Committee, Federal Drug Administration
2010-2012
Antimicrobial Stewardship Working Group, SHEA/IDSA
2011-2014
Public Policy and Government Affairs Committee, SHEA
2013-2014
Expert Panel, Compendium for Strategies to Prevent, Healthcare Associated Infections in Acute Care, Hospitals, 2014 Updates, SHEA/IDSA
2014-
Health Care Systems Subcommittee, NIH Collaboratory
2014-2015
Expert consultant, Trans-Atlantic Task Force Antimicrobial Resistance (TATFAR)
2014-2015
Antimicrobial Stewardship Committee, SHEA
2014-
Patient Safety Committee NQF
2016-2018
Leadership Consortium, NQF
2017-2019
Technical Expert Panel, AHRQ Safety Program for Improving Antibiotic Use
2017-
Consensus Standards Approval Committee (CSAC), NQF
2018-
IDSA Task Force on Sepsis
Professional Societies
1976-
Fellow, American College of Physicians(ACP)
1977-
Fellow, IDSA
1978-
Member, American Society for Microbiology
1982-
Fellow, SHEA
1983-
Member, Association for Professionals in Infection Control and Epidemiology
1989-
Member, Texas Infectious Diseases Society
2011-
Member, Society Critical Care Medicine
Editorial Activities
Ad hoc reviewer
· PLoS Medicine
· JAMA
· Clinical Infectious Diseases
· American Journal Infection Control
· Infection Control Hospital Epidemiology
· Critical Care Medicine
· Open Forum Infections Diseases
· American Journal of Medical Sciences
Honors
1967
Alpha Epsilon Delta (Honorary Pre-Medical Society), President's Scholarship Award, Ohio State University
1983-1986
Outstanding Education Award, University of Texas Health Science Center, Houston
1995
Physician of the Year, Memorial Hermann Southwest
1982, 1983, 1985
Best 4th Year Elective
1989, 1995
University of Texas Health Science Center, Houston
1993
Watanakunakorn Annual Clinician Award, IDSA
2006-2007
Award for Excellence, Montana Residency Program (affiliated with U. Washington)
2011-2014, 2016-2017
John S Dunn Sr. Outstanding Teaching Award, Memorial Hermann Southwest Residency (Affiliated Texas A&M)
2013
Clinical Excellence Award, HealthTrust Purchasing Group
2014
Excellence in Partnering-Domestic, Centers for Disease Control and Prevention (CDC)
2016
Antimicrobial Stewardship Program Award, City of Houston Health Department
2018
Albert Nelson Marquis Lifetime Achievement Award, Marquis Who’s Who
Report of Funded Projects
Past funded projects
2005-2006
Robert Wood Johnson Foundation Positive Deviance MRSA Prevention Partnership: Use the method called Positive Deviance to redesign care to reduce MRSA infections.
Role: Co-Investigator
2009-2013
Reduce MRSA, Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program and the Agency for Healthcare Research and Quality (AHRQ) A three-arm randomized cluster trial to determine best intervention to reduce infections in the ICU. This involved 43 hospitals and 74 ICUs.
Role: Co-Investigator
2013-2015
Optimizing Pre-Operative Antibiotic Prophylaxis in Cardiac and Orthopedic Procedures. AHRQ contract # HHSA2902006100021I. Develop a best practice algorithm to reduce complex infections in orthopedic and cardiac surgery across 20 hospitals
Role: Co-Investigator
2010-2012
CDC/IHI Antimicrobial Stewardship Project, Public Health Foundation. Goal to develop a driver diagram outlying factors necessary to optimize antimicrobial use and improve outcomes while reducing adverse events. This was an 8-hospital project and measurements were developed to determine impact
Role: PI
2016-2017
Estimating the national burden of sepsis using electronic health record data, NIH / CDC 3U54CK000172-05S1. The goal of this project is to utilize electronic health record (EHR) data from a large network of diverse hospitals to estimate trends in sepsis burden using the surveillance definition that we have developed and validated.
Role: Co-Investigator
Current funded projects
2013-
ABATE, NIH ABATE Infection Trial 1 UH2 AT007769-01. Goals to determine is CHG bathing in non-critical care reducing healthcare-associated infections. This is a 53 hospital in over 190 units in a 2 arm randomized cluster trial. Trial complete data being analyzed.
Role: Co-Investigator
2015-
Swap Out, CDC 2016-2020 1U54 CK000484-01 Epicenter IV: Harvard Pilgrim-UCI Center for HAI Prevention. Swap Out Trial: 2 arm randomized trial in adult ICUs 140 hospitals: arm 1 mupirocin intranasal plus CHG bathing; arm 2 iodophor intranasal with CHG bathing. Key outcomes S aureus clinical cultures, all cause bacteremia, and emergence of resistance to mupirocin and iodophor
Role: Co-Investigator
2016- T
he CLUSTER Trial: Cluster Linkage Using Statistics to Trigger and Evaluate Response. CDC 2016-2020 1U54 CK000484 Epicenter IV Large Multicenter. Project. This supplemental grant is to conduct a cluster randomized trial of 80 hospitals to reduce the size and duration of hospital outbreaks using a space-time statistical software tool for alerting clusters
Role: Co-Investigator
2016-
INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients - The INSPIRE-ASP Trial. CDC SHEPheRD Task Order 200-2011-42037 TO 2016-003. The goal of this project is to conduct a cluster randomized trial of 40 hospitals with the goal of reducing empiric extended spectrum antibiotics in non-critically ill adults hospitalized with pneumonia and urinary tract infection. The trial compares routine care to a point-of-care smart tool providing real-time probabilities of MDRO infection in this population
Role: Co-Investigator
2016-
Detection and Response CRE and C. difficile. CDC Grant Epidemiological and Laboratory Capacity (ELC), K1 (Focus on Detections and Response), K2 (Focus on Coordinated Prevention and Stewardship). Goal to collect CRE and C difficile isolates across great Houston to perform whole genome sequencing and other molecular studies for tracking resistance and infections across the continuum of care. Stewardship opportunities will be identified along with suggested interventions
Role: Co-Investigator
2018-
Surveillance of Multidrug-Resistant Emerging Healthcare Pathogens, Texas Medical Center Health Policy Institute grant
To establish a real-time surveillance system for Candida species isolated from hospitalized patients with bloodstream infection from at least 20 participating hospitals in the Texas Medical Center and surrounding Houston hospitals
To create a reproducible, high-throughput analysis platform for whole genome sequencing of Candida species
Disseminate results of the whole genome surveillance system to local, state, and national thought leaders
Role: Co-PI
Report of Local Teaching and Training
Clinical supervisory and training responsibilities
1978-2003
Medical Students, Residents, and Fellows
20-30 hours per week
Attending rounds and didactic lectures and conferences
Memorial Hermann Southwest
2006-2007
Residents
5-10 hours per week
Attending rounds and didactic lectures
Billings Clinic
2009-
Medical Students and Residents
20 hours per week
Attend on inpatient teaching service and consult on infectious diseases cases.
Memorial Hermann Southwest
2017-
Pharmacy Residents
5 hours per week
Meet either by conference call or in person to oversee pharmacy research projects
Local and Regional Invited Presentations
1988
The Economics of Prescribing, Annual Session
Texas Academy of Family Practice
1992
The Use of Biologics in the Treatment Prevention of Infections
Grand Rounds Memorial Hermann Healthcare System
1993
Case Management from a Physician's Perspective: Improving Communication
Case Management Society of America, Houston Gulf Coast Chapter
1996
Update on Infection Control
Texas Infectious Diseases Society Annual Meeting
1996
Emerging Problems in Infectious Diseases
Grand Rounds, Memorial Healthcare System
1997
AIDS Update
Annual Meeting, Texas Academy of Family Practice
1998
The Economics of Prescribing
Annual Session, Texas Academy of Family Practice
2000
Medication Error Reduction
Grand Rounds, Memorial Hermann Healthcare System
2002
Bioterrorism, A Common-Sense Approach
Grand Rounds, Memorial Hermann Southwest
2002
Antimicrobial Resistance: How Bad Is It?
Grand Rounds Memorial Hermann Healthcare
2002
MRSA in Healthcare
Texas Society of Infection Control
2003
Antimicrobial Stewardship
Texas Society of Infection Control
2005
Community Acquired MRSA
Texas Public Health Association
2005
Molecular Testing and Outbreak Investigation
Texas Society of Infection Control
2007
Sepsis: Review of Current and Emerging Evidence
Medicine Grand Rounds Baylor University Medical Center
2007
Do MRSA Program Work? Determining the Value of Hospital-Associated MRSA Surveillance and Prevention Programs
Third Annual Reducing HAI Conference
2008
Colonization and Decolonization MRSA
Texas Department of Health
2009
ABCs of C. difficile: The Role of Antimicrobial Use and Resistance
Texas Public Health Association
2009
Influenza Vaccination; Evidence and Knowledge
George Mason University Policy Forum
2009
Reducing Hospital Infections through Design
Houston APIC meeting
2010
Compendium 2010
Florida Professionals in Infection Control
2011
Antimicrobial Stewardship Overview: An Urgent Patient Safety Imperative
Texas Infectious Diseases Society Annual Meeting
2011
Infection Prevention and Control for Outpatient Settings
Memorial Hermann Residency Meeting
2011
Antimicrobial Stewardship: A Call to Action
St Luke’s Episcopal Hospital Internal Medicine Grand Rounds Houston
2011
Antimicrobial Stewardship: An Urgent Patient Safety Intervention
MD Anderson Grand Rounds Houston
2012
Antimicrobial Resistance and Stewardship
Presbyterian Hospital Dallas
2012
Antimicrobial Stewardship: Goals and Interventions
Texas Hospital Association
2012
Immunization of Healthcare Personnel
Immunization Partnership Meeting
2013
Starting or Re-Engineering Your Antimicrobial Stewardship Program
George Health Department
2013
Antimicrobial Stewardship: A Call to Action
Webinar state of Florida
2013
Antimicrobial Stewardship: Is the Dawn of the Post Antibioitc Era?
Webinar State of Tennessee
2013
Healthcare Associated Infections (HAIs): Unique Aspects of Infection Prevention in Neonates and Children
Grand Rounds University of Alabama Medical School
2013
Trends in HAIs: The HCA Experience Horizontal versus Horizontal Intervention
APIC Greater Kansas City Chapter
2013
Universal Decolonization in the ICU: The New Standard of Care Horizontal versus Vertical
Grand Rounds Columbia Presbyterian Hospital
2013
Vaccination of Healthcare Worker in the Office Setting
Dallas Fort Worth APIC Meeting
2014
Antimicrobial Stewardship: A Call to Action
Webinar State of Pennsylvania
2014
Antimicrobial Stewardship: A Call to Action
Nevada state-wide stewardship kickoff, Las Vegas
2015
Engaging Stakeholders: The Houston Experience
Houston Antimicrobial Stewardship Symposium
2015
Antimicrobial Resistance: 2105 Update
Annual Infectious Diseases Meeting Corpus Christi Texas
2015
Infectious Diseases Bootcamp
HCA Nashville meeting
2015
Vertical versus Horizontal Interventions to Reduce HAIs
Texas Infectious Diseases Society Annual Meeting
2015
Universal Decolonization Horizontal versus Vertical Interventions to Reduce HAIs
Iowa State Public Health Conference
2015
Implementing Effective Infection Prevention in Small Community Settings
Nebraska Infectious Diseases Annual Meeting
2016
Antimicrobial Stewardship for Primary Care
Houston Methodist Healthcare
2016
Changing Prescribing Behavior
Houston Antimicrobial Stewardship Symposium
2016
C difficile Infections: Diagnosis, Treatment, and Prevention
Texas Department of Health
2016
Decolonization to Reduce HAIs
Grand Rounds Baylor College of Medicine
2016
Sepsis Update
Texas Infectious Diseases Society Annual Meeting
2016
Use of Molecular Epidemiology in the Evaluation of Outbreaks
Michigan APIC Meeting
2017
Reducing HAIs: The HCA Story
Dallas Fort Worth APIC Chapter meeting
2017
Stewardship to Combat Antimicrobial Resistance: Translating Science into Practice
Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference
2017
Antimicrobial Resistance: A Call to Action
Scott and White Infectious Diseases Conference Waco Texas
2018
Strengthening Collaboration to Tackle Antimicrobial Resistance
Healthcare Innovation Forum Houston
2018
Top 10 Papers in Infectious Diseases
Texas Infectious Diseases Society Annual Meeting
2018
The Synergy Between Diagnostic and Antimicrobial Stewardship
Annual Rocky Mountain Pus Club Summer Annual Meeting 2018
National and International
1979
Orthopedic Infections
APIC annual meeting
1981
Nocardia in the Compromised Host
American Thoracic Society annual meeting
1982
Prevention of Wound Infections
American College of Foot Surgeons annual meeting
1984
Employee Illness
College of American Pathology annual meeting
1985
Cost Effective Application of the CDC Guidelines for Employee Health
APIC annual meeting
1986
Quality Assurance in Home IV Antibiotics
National Association for Home Care annual meeting
1989
General Overview of Home IV Antibiotic Therapy
Annual International Congress on Chemotherapy
1992
Infection Control
National Association of Orthopedic Nurses
1994
Newer Antibiotics
IDSA Annual Meeting
1997-2000
Infectious Diseases Case Management
IDSA Annual Meeting
2001
Update on Hepatitis and HIV
American College of Foot Surgeons annual meeting
2005
Save 100,000 Lives Campaign
IDSA Annual Meeting
2009
A multi-pronged approach to reduce MRSA in Community Hospitals
SHEA annual meeting
2009
Prevention of Central-Venous Catheter-Associated Bloodstream Infections: Striving for Zero
APIC Annual Meeting
2010
Can We Eliminate HAIs?
International Intensive Care and Emergency Medicine Meeting
2011
Why We Need Antimicrobial Stewardship: The International Perspective
International Intensive Care and Emergency Medicine Meeting
2010
Implementation of a Successful Seasonal Influenza Vaccine Strategy in a Large Healthcare System
Decennial Meeting
2010
Preventing Surgical Site Infections: Beyond Core Measures
AORN Annual Meeting
2010
Preventing Surgical Site Infections
APIC Annual Meeting
2010
Influenza Vaccination of Health Care Personnel: Should Vaccination be Mandatory?
IDSA Annual Meeting
2010
Components of a Practical Implementation Approach: Using a “Driver Diagram” for Antimicrobial Stewardship
IDSA Annual Meeting
2011
Challenges of Managing H1N1 within a Large Healthcare System
IDSA Seasonal and Pandemic Meeting
2011
Engaging the C-suite: The Ethical and Financial case for Quality
SHEA Annual Meeting
2011
Why do We Need Antimicrobial Stewardship?
International Intensive Care and Emergency Medicine
2011
Stewardship and Informatics
IDSA Annual Meeting
2012
Scaling Up from One Hospital to a Multi-Facility System
SHEA Annual Meeting
2012
Stewardship in the OR: is SCIP Enough?
SHEA Annual Meeting
2012
Implementing Sustainable Surveillance and Prevention Programs Outside the Critical Care Units with Limited Resources
ID Week Annual Meeting
2013
Vertical versus Horizontal Interventions to Prevent HAIs
APIC Annual Meeting
2013
The HCA Journey
NIH Collaboratory Grand Rounds
2014
Sepsis: The Evolving Science
APIC Annual Meeting
2014
Thorny Issues in Infection Prevention
ID Week Annual Meeting
2014
Practical CHG Bathing: Implementation Pearls
ID Week Annual Meeting
2015
Implementing the STOP SSI Bundle/Algorithm
SHEA Annual Meeting
2015
Antimicrobial Stewardship: Physician Engagement and Behavior
SHEA Annual Meeting
2015
Options for Nasal Decolonization of S aureus
SHEA Annual Meeting
2015
How to Keep CRE at the Hospital Door
Infection Prevention Society UK
2016
The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance: First Results of Antimicrobial Prescribing in United States Hospitals
ECCMID Annual Meeting Amsterdam
2016
Data Sharing in Pragmatic Trials: Balancing Transparency and Health System Privacy
NIH Collaboratory Grand Rounds
2017
Frequent barriers in Antimicrobial Stewardship Programs
ID Week Annual Meeting
2017
ABATE Infection Project Preliminary Results
NIH Collaboratory Grand Rounds
2017
Changing Prescriber Behavior
National Institute for Animal Agriculture Annual Meeting
2018
The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance: Results of Antimicrobial Prescribing in US Hospitals
ECCMID Annual Meeting Madrid
2018
Nasal Decolonization: What Agent is Most Effective to Prevent Surgical Site Infections
APIC Annual Meeting
2018
Antimicrobial Stewardship: Implementing an Effective Inpatient Program
AACC Annual Scientific Meeting 2018
2018
Controversies in Sepsis from the ID Perspective
ID Week Annual Meeting
2019
Core Elements of Stewardship Program: Commitment, Action, for Policy and Practice, Tracking and Reporting, and Educational Needs
American College of Healthcare Executives Annual Meeting
Report of Clinical Activities and Innovation
Current Licensure and Certification
1975-
Texas Medical License
2005-
Montana Medical License
1975-
Certification in Internal Medicine
Amercian Board of Internal Medicine
1984-
Certification in Infectious Diseases
Amercian Board of Internal Medicine
Practice Activities
1978-2003
Infectious Diseases Consult Teaching Service
~100 consults/month
Patient load 25-30 patients/day
Clinical Activity: Attending physician on inpatient infectious diseases service, rounding, new consults, teaching conferences
Memorial Hermann Southwest
2006-2007
Infectious Diseases Service
25-30 consults/month
Patient load ~10 patients/day
Includes inpatient and outpatient
Formal teaching rounds and microbiology rounds
Billings Clinic
2009-
Infectious Diseases Consultation Teaching Service
20-25 consults/month
Patient load ~5 day
Formal rounding 2 days per week for 2-3 hours in addition to consults and rounding as needed
Rounding with Clinical Infectious Diseases pharmacist with Intensivists and residents
Memorial Hermann Southwest
2018-
Case presentations and review
Quarterly literature review
Department of Population Medicine, Harvard Pilgrim Health
Care Institute
Clinical Innovations
2016-
INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients - The INSPIRE-ASP Trial
The goal of this project is to conduct a cluster randomized trial of 40 hospitals with the goal of reducing empiric extended spectrum antibiotics in non-critically ill adults hospitalized with pneumonia and urinary tract infection. The trial compares routine care to a point-of-care smart tool providing real-time probabilities of MDRO infection in this population. This is using real-time precision medicine to improve outcomes which is innovative.
Report of Scholarship
Peer-reviewed Publications
1. Schindler WJ, Hutchins MO, Septimus EJ; Growth hormone secretion and control in the mouse. Endocrinology 1972; 91:483-490 PMID 4644228
2. Septimus EJ, Awe R, Greenberg S, Raleigh J; Acute tuberculous pneumonia. Chest 1977; 71:774-776
3. Wallace RJ Jr., Septimus EJ, Musher DM, Martin RR; Disc diffusion susceptibility testing of Nocardia. J Infect Dis 1977; 135:568-576 PMID 85324
4. Vainrub B, Musher DM, Young EJ. Septimus EJ, Travis LL. Percutaneous drainage of lung abscesses. Am Rev Resp Dis. 1978; 117: 153-160 PMID 413460
5. Septimus EJ, Musher DM. Osteomyelitis: recent clinical and laboratory aspects. Orthop Clin Nroth Am 1979; 347:347-359 PMID 377137
6. Wallace RJ, Jr., Septimus EJ, Musher DM, Berger MB, Martin RR. Treatment of experimental nocardiosis in mice: comparison of amikacin and sulfonamide. J Infect Dis. 1979;140(2):244-248. PMID 383855
7. Septimus EJ. Osteomyelitis secondary to traumatic injury or surgery: Diagnosis, treatment, and prevention. Quart Rev; 1979; 5:20-24
8. Miller SI, Wallace RJ, Jr., Musher DM, Septimus EJ, Kohl S, Baughn RE. Hypoglycemia as a manifestation of sepsis. Am J Med. 1980;68(5):649-654. PMID 6990758
9. Greenberg SB, Taber L, Septimus E, Kohl S, Puck J, Bryan RN. Computerized tomography in brain biopsy-proven herpes simplex encephalitis. Early normal results. Arch Neurol. 1981;38(1):58-59. PMID 6970031
10. Wallace RJ, Jr., Musher DM, Septimus EJ, McGowen J E, Jr, Quinones FJ, Wiss K, Vance PH, Trier PA. Haemophilus influenzae infections in adults: characterization of strains by serotypes, biotypes, and beta-lactamase production. J Infect Dis. 1981;144(2):101-106. PMID 6974204
11. Lampe RM, Baker CJ, Septimus EJ, Wallace RJ, Jr. Cervicofacial nocardiosis in children. .J Pediatr 1981;99(4):593-595. PMID 7277103
12. Wallace RJ, Jr., Septimus EJ, Williams TW, Jr., Conklin RH, Satterwhite TK, Bushby MB, Hollowell DC. Use of trimethoprim-sulfamethoxazole for treatment of infections due to Nocardia. Rev Infect Dis. 1982 4:315-325. PMID:6981158
13. Hawes, S., Whigham, T., Septimus, EJ, Musher, DM, Young, E., Sugarman, B. Emphysematous Pyelonephritis. Infect Surg 1983; 2:191-196
14. Septimus EJ. Seroprevalence of hepatitis B markers in health care workes at ateaching medicla center and two commuinty hospitals. Ad Therapy 1984; 1:215-220
15. Vartian CV, Septimus EJ. Intra-abdominal infections in the elderly: diagnosis and management. Geriatrics 1986; 41:51-56. PMID: 3943722
16. Septimus EJ. Cost-effective application of the Centers for Disease Control Guideline for Infection Control in Hospital Personnel. Am J Infect Control 1985; 13:224-227. PMID 2998232
17. Johnson PC, Sarosi GA, Septimus EJ, Satterwhite TK. Progressive disseminated histoplasmosis in patients with the acquired immune deficiency syndrome: a report of 12 cases and a literature review. Semin Respir Infect 1986; 1:1-8. PMID 3317594
18. Chapel TA, Riley HD, Septimus EJ. Cutaneous signs of infection. Patient Care 1988; 22:185-218
19. Vartian C, Septimus EJ. Pyomyositis in an intravenous drug user with human immunodeficiency virus. Arch Intern Med 1988; 148:2689-2690. PMID 3196130
20. Vartian CV, Septimus EJ. 1989. Endophthalmitis due to Pasteurella multocida and CDC EF-4. J Infect Dis 1989; 160:733. PMID 2794571
21. Septimus EJ. Nosocomial bacterial pneumonias. Sem Resp Infect 1989; 4:245-252
22. Vartian CV, Septimus EJ. Septic bursitis caused by gram-negative bacilli. J Infect Dis 1989; 160:908-909. PMID 2681439
23. Vartian CV, Septimus EJ. Osteomyelitis caused by Vibrio vulnificus. J Infect Dis 1990; 161:363-364 PMID 2299219
24. Williams DN, Septimus EJ. Use of newer devices for home intravenous antibiotic therapy. 1990; 2:1-4
25. Vartian CV, Septimus EJ. Soft-tissue infection caused by Edwardsiella tarda and Aeromonas hydrophila. 1990; J Infect Dis 161:816. PMID 2319177
26. Vartian CV, Septimus EJ. Tricuspid valve group B streptococcal endocarditis following elective abortion. Rev Infect Dis 1991; 13:997-998. PMID 1962116
27. Murphey DK, Septimus EJ, Waagner DC. Catfish-related injury and infection: report of two cases and review of the literature. Clin Infect Dis 1992; 14:689-693. PMID 1562661
28. Steiner JL, Septimus EJ, Vartian CV. Infection of the psoas muscle secondary to Streptococcus pneumoniae infection. Clin Infect Dis 1992; 15:1047-1048. PMID 1457639
29. Vartian CV, Septimus EJ. Meningitis caused by group B streptococcus in association with cerebrospinal rhinorrhea. Clin Infect Dis 1992; 14:1261-1262. PMID 1623084
30. Septimus EJ. Helicobacter pylori infection. Houston J Gastroenterol 1994; 3:3-5.
31. Vartian CV, Cabiness T, Septimus EJ. Olecranon bursitis caused by Mycobacterium avian complex: reprt of two cases. Infect Dis Clin Practice 1996; 5:74-76
32. Vartian CV, Septimus EJ. Bronchoesophageal fistula due to Mycobacterium tuberculosis and cytomegalovirus in a patient with AIDS. Clin Infect Dis 1996; 22:581. PMID 8852989
33. Douglass ET, Septimus EJ, Vartian CV. Late prosthetic joint infections due to Group B and Group G Streptococcus; case reports and review of the literature. Infect Dis Clin Pract 1997; 6:489-494 ISSN 1056-9103
34. Ericsson CD, Long J, Septimus E. African Tick-Bite Fever: A Case Report. Journal of Travel Medicine 1997; 4:197-197 ISSN 1195-1982
35. Vartian CV, Septimus EJ. Genital Ulceration in a Young Woman with Infectious Mononucleosis. Infect Dis Clin Practice 1999; 8:354-355. ISSN 1056-9103
36. El Sahly HM, Septimus E, Soini H, Septimus J, Wallace RJ, Pan X, Williams-Bouyer N, Musser JM, Graviss EA. Mycobacterium simiae pseudo-outbreak resulting from a contaminated hospital water supply in Houston, Texas. Clin Infect Dis 2002; 35:802-807. PMID 12228816
37. Gonzalez OY, Musher DM, Brar I, Furgeson S, Boktour MR, Septimus EJ, Hamill RJ, Graviss EA. Spectrum of bacille Calmette-Guerin (BCG) infection after intravesical BCG immunotherapy. Clin Infect Dis 2003; 36:140-148. PMID 12522745
38. Christenson, M., Hitt, J.A., Septimus, E.J., and Iversen, N. Improving patient safety: Resource availability and application for reducing healthcare-associated infections in community hospitals. Infect Control Hosp Epidemiol 2006; 27:245-251 doi:10.1086/500370
39. Hitt JA, Septimus EJ. Weathering the infecious storm in intensive care. Advance Resp Care 2005; 14:22-23
40. Berenholtz SM, Pronovost PJ, Ngo K, Barie PS, Hitt J, Kuti JL, Septimus E, Lawler N, Schilling L, Dorman T. Developing Quality Measures for Sepsis Care in the ICU. Joint Commission Journal on Quality and Patient Safety 2007; 33:559-568. DOI: 10.1016/S1553-7250(07)33060-2
41. Mohr JF, McKinnon PS, Peymann PJ, Septimus E, Okhuysen PC. A retrospective comparative evaluation of dysglycemia in hospitalized patients receiving gatofloxacin, levofloxacin, ciprofloxacin, or ceftriaxone. Pharmacotherapy 2005; 25:1303-13609 PMID 161851732
42. Septimus EJ, Hitt J. Ventillator-associated pneumonia: prevention. Diagnosis, and treatment. Managing Infection Control. 2006; 6:34-41 PMID 16504137
43. Septimus JD, Septimus EJ. Prostatitis Due to Candida albicans. Infect Dis in Clin Practice 2006; 14:239. DOI: 10.1097/01.idc.0000205843.05269.50
44. Polgreen PM, Septimus EJ, Parry MF, Beekmann SE, Cavanaugh JE, Srinivasan A, Talbot TR. Relationship of influenza vaccination declincation statement and influenza vaccination rates in 22 US hospitals. Infect Control Hosp Epidemiol 2008; 29:675-677 PMID 18564904
45. Septimus EJ. International conference on health care-associated bloodstream infections. Am J Infect Control 2008; 36: S167-170. PMID:19084145
46. Kuper KM, Septimus EJ. Health-care-associated infections: the legislative perspective and the pharmacist's role. 2009;Am J Health Syst Pharm 66:488-494. PMID: 19233997
47. Septimus EJ, Kuper KM. 2009. Clinical challenges in addressing resistance to antimicrobial drugs in the twenty-first century. Clin Pharmacol Ther 86:336-339. PMID 19571803
48. Cormier S, Septimus E, Moody J, Perlin J. A community health system response to the pandemic of novel H1N1. World Medical and Health Policy J 2009; 1:35-46 DOI: 10.2202/1948-4682.1012
49. Platt R, Takvorian SU, Septimus E, Hickok J, Moody J, Perlin J, Jernigan JA, Kleinman K, Huang SS. Cluster randomized trials in comparative effectiveness research: randomizing hospitals to test methods for prevention of healthcare-associated infections. Med Care 2010; 48: S52-57. PMID: 20473200
50. Septimus E, Moody J. Strategies to eliminate healhcare-associated central-line-associated bloodstream infections in adults. Managing Infect Control 2010;10:48-58
51. Nicogossian A, Ebadirad N, Zimmerman T, Septimus E. Influenza immunization:synthesizing and communoicating the evidence. World Medical and Health Policy J 2010; 2:1-34 DOI: 10.2202/1948-4682.1090
52. Polgreen PM, Septimus E, Talbot TR, Beekmann SE, Helms C. Results of a national survey of infectious diseases specialists regarding influenza vaccination programs for healthcare workers. Infect Control Hosp Epidemiol 2010; 31:1063-1065. PMID: 20804373
53. Talbot TR, Babcock H, Caplan AL, Cotton D, Maragakis LL, Poland GA, Septimus EJ, Tapper ML, Weber DJ. Revised SHEA position paper: influenza vaccination of healthcare personnel. Infect Control Hosp Epidemiol 2010; 31:987-995. PMID: 20807037
54. Nicogossian A, Kloiber O, Zimmerman T, Grigoriev AI, Koizumi N, Mayer JD, Heineman-Pieper J, Doarn CR, Septimus EJ, Jacobs W, Beritashvili T. 2010. Translational Research, Evidence-Based Medicine and Medical Policy. World Medical & Health Policy 2010; 2:1-5. DOI: 10.2202/1948-4682.1145
55. Septimus EJ, Owens RC, Jr. Need and potential of antimicrobial stewardship in community hospitals. Clin Infect Dis 2011; 53 Suppl 1: S8-s14. PMID: 21795728
56. Septimus EJ, Perlin JB, Cormier SB, Moody JA, Hickok JD. A multifaceted mandatory patient safety program and seasonal influenza vaccination of health care workers in community hospitals. JAMA 2011; 305:999-1000. PMID: 21386077
57. Spellberg B, Blasser M, Guidos RJ, Boucher HW, Bradley JS, Gerding D, Rex J, Lynnfield R, Septimus ES, Tenover F, Gilbert D. . Combating Antimicrobial Resistance: Policy Recommendations to Save Lives. Clin Infect Dis 2011; 52:S397-S428. DOI: 10.1093/cid/cir153
58. Nicogossian A, Zimmerman T, Kloiber O, Septimus EJ. Anti-Microbial Drug Resistance: A Human Disaster in the Making. World Medical & Health Policy 2011; 3:1-5. DOI: 10.2202/1948-4682.1172
59. Moody J, Cosgrove SE, Olmsted R, Septimus E, Aureden K, Oriola S, Patel GW, Trivedi KK. . Antimicrobial stewardship: a collaborative partnership between infection preventionists and healthcare epidemiologists. Infect Control Hosp Epidemiol 2012; 33:328-330. PMID 22418626
60. Moody J, Septimus E, Hickok J, Huang SS, Platt R, Gombosev A, Terpstra L, Avery T, Lankiewicz J, Perlin JB. 2013. Infection prevention practices in adult intensive care units in a large community hospital system after implementing strategies to reduce health care-associated, methicillin-resistant Staphylococcus aureus infections. Am J Infect Control 2013; 41:126-130. PMID 22748841
61. Talbot TR, Babcock H, Cotton D, Maragakis LL, Poland GA, Septimus EJ, Tapper ML, Weber DJ. The use of live attenuated influenza vaccine (LAIV) in healthcare personnel (HCP): guidance from the Society for Healthcare Epidemiology of America (SHEA). Infect Control Hosp Epidemiol 2012; 33:981-983. PMID 22961016
62. Perlin JB, Hickok JD, Septimus EJ, Moody JA, Englebright JD, Bracken RM. A bundled approach to reduce methicillin-resistant Staphylococcus aureus infections in a system of community hospitals. J Healthc Qual 2013; 35:57-68; quiz 68-59. PMID 23648079
63. Perlin JB, Septimus EJ, Cormier SB, Moody JA, Hickok JD, Bracken RM. Developing a program to increase seasonal influenza vaccination of healthcare workers: lessons from a system of communnity hospitals. J Healthc Qual 2013; 35:5-15. PMID 23470232
64. Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R, Program CDCPE, Network AD, Healthcare-Associated Infections P. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med 2013; 368:2255-2265. PMID 23718152
65. Nicogosssian A, Stabile B, Kloiber O, Septimus E, Zimmerman T. A Look Back at 2012: A Year of Transition. World Medical & Health Policy 2013; 5:1-3. DOI: 10.1002/wmh3.16
66. Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess D, Hill NS, Horan T, Kollef M, Levy M, Septimus E, VanAntwerpen C, Wright D, Lipsett P. Developing a new, national approach to surveillance for ventilator-associated events. Crit Care Med 2013 41:2467-2475. PMID: 24162674
67. Septimus E, Yokoe DS, Weinstein RA, Perl TM, Maragakis LL, Berenholtz SM. Maintaining the momentum of change: the role of the 2014 updates to the compendium in preventing healthcare-associated infections. Infect Control Hosp Epidemiol 2014;35:460-463. PMID 24709714
68. Septimus EJ, Hayden MK, Kleinman K, Avery TR, Moody J, Weinstein RA, Hickok J, Lankiewicz J, Gombosev A, Haffenreffer K, Kaganov RE, Jernigan JA, Perlin JB, Platt R, Huang SS. Does chlorhexidine bathing in adult intensive care units reduce blood culture contamination? A pragmatic cluster-randomized trial. Infect Control Hosp Epidemiol 2014; 35 Suppl 3:S17-22. PMID 25222893
69. Huang SS, Septimus E, Avery TR, Lee GM, Hickok J, Weinstein RA, Moody J, Hayden MK, Perlin JB, Platt R, Ray GT. 2014. Cost savings of universal decolonization to prevent intensive care unit infection: implications of the REDUCE MRSA trial. Infect Control Hosp Epidemiol 2014; 35 Suppl 3:S23-31. PMID 25222894
70. Septimus E, Weinstein RA, Perl TM, Goldmann DA, Yokoe DS. Approaches for preventing healthcare-associated infections: go long or go wide? Infect Control Hosp Epidemiol 2014; 35:797-801. PMID 24915206
71. Septimus E. Antimicrobial stewardship-qualitative and quantitative outcomes: the role of measurement. 2014; Curr Infect Dis Rep 16:433. PMID 25230602
72. Jacobs DM, Kuper K, Septimus E, Arafat R, Garey KW. 2016. Assessment of Antimicrobial Stewardship Activities in a Large Metropolitan Area. J Pharmacy Practice 2016; 29:188-193. PMID 25312262
73. Braykov NP, Morgan DJ, Schweizer ML, Uslan DZ, Kelesidis T, Weisenberg SA, Johannsson B, Young H, Cantey J, Srinivasan A, Perencevich E, Septimus E, Laxminarayan R. Assessment of empirical antibiotic therapy optimisation in six hospitals: an observational cohort study. Lancet Infect Dis 2014; 14:1220-1227. PMID 25455989
74. Johnson KE, Tachibana C, Coronado GD, Dember LM, Glasgow RE, Huang SS, Martin PJ, Richards J, Rosenthal G, Septimus E, Simon GE, Solberg L, Suls J, Thompson E, Larson EB. A guide to research partnerships for pragmatic clinical trials. 2014; Bmj 349:g6826. PMID 25446054
75. Septimus E, Green L, Klompas M. 2015. Ventilator-associated events: a broader perspective. Crit Care Med 2015; 43:e59-61. PMID 25599509
76. Lantos JD, Wendler D, Septimus E, Wahba S, Madigan R, Bliss G. Considerations in the evaluation and determination of minimal risk in pragmatic clinical trials. Clin Trials 2015; 12:485-493. PMID 26374686
77. Schweizer ML, Chiang HY, Septimus E, Moody J, Braun B, Hafner J, Ward MA, Hickok J, Perencevich EN, Diekema DJ, Richards CL, Cavanaugh JE, Perlin JB, Herwaldt LA. Association of a bundled intervention with surgical site infections among patients undergoing cardiac, hip, or knee surgery. Jama 2015; 313:2162-2171. PMID 26034956
78. Larson EB, Tachibana C, Thompson E, Coronado GD, DeBar L, Dember LM, Honda S, Huang SS, Jarvik JG, Nelson C, Septimus E, Simon G, Johnson KE. Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthcare 2016; 4:138-141. DOI: 10.1016/j.hjdsi.2015.07.005
79. Huang SS, Septimus E, Hayden MK, Kleinman K, Sturtevant J, Avery TR, Moody J, Hickok J, Lankiewicz J, Gombosev A, Kaganov RE, Haffenreffer K, Jernigan JA, Perlin JB, Platt R, Weinstein RA. Effect of body surface decolonisation on bacteriuria and candiduria in intensive care units: an analysis of a cluster-randomised trial. Lancet Infect Dis 2016; 16:70-79. PMID 26631833
80. Kelesidis T, Braykov N, Uslan DZ, Morgan DJ, Gandra S, Johannsson B, Schweizer ML, Weisenberg SA, Young H, Cantey J, Perencevich E, Septimus E, Srinivasan A, Laxminarayan R. Indications and Types of Antibiotic Agents Used in 6 Acute Care Hospitals, 2009-2010: A Pragmatic Retrospective Observational Study. Infect Control Hosp Epidemiol 2016; 37:70-79. PMID 26456803
81. Septimus EJ, Schweizer ML. Decolonization in Prevention of Health Care-Associated Infections. Clin Microbiol Rev 2016; 29:201-222. PMID 26817630
82. Septimus E, Hickok J, Moody J, Kleinman K, Avery TR, Huang SS, Platt R, Perlin J. Closing the Translation Gap: Toolkit-based Implementation of Universal Decolonization in Adult Intensive Care Units Reduces Central Line-associated Bloodstream Infections in 95 Community Hospitals. Clin Infect Dis 2016; 63:172-177. PMID 27143669
83. Barlam TF, Cosgrove SE, Abbo LM, MacDougall C, Schuetz AN, Septimus EJ, Srinivasan A, Dellit TH, Falck-Ytter YT, Fishman NO, Hamilton CW, Jenkins TC, Lipsett PA, Malani PN, May LS, Moran GJ, Neuhauser MM, Newland JG, Ohl CA, Samore MH, Seo SK, Trivedi KK. . Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 2016; 62:e51-77. PMID 27143669
84. Septimus E, Moody J. Prevention of device-related healthcare-associated infections. f1000 Research 2016; 5:65 DOI: 10.12688f1000research.7496.1
85. Hayden MK, Lolans K, Haffenreffer K, Avery TR, Kleinman K, Li H, Kaganov RE, Lankiewicz J, Moody J, Septimus E, Weinstein RA, Hickok J, Jernigan J, Perlin JB, Platt R, Huang SS. Chlorhexidine and Mupirocin Susceptibility of Methicillin-Resistant Staphylococcus aureus Isolates in the REDUCE-MRSA Trial. J Clin Microbiol 2016; 54:2735-2742. PMID 27558180
86. Jinadatha C, Septimus EJ. 2017. Prevention of Health Care-Associated Infections in an Era of Public Reporting. Tex Med 2017; 113:42-47. PMID 28207077
87. Septimus EJ, Albrecht HH, Solomon G, Shea T, Guenin EP. . Extended-Release Guaifenesin/Pseudoephedrine Hydrochloride for Symptom Relief in Support of a Wait-and-See Approach for the Treatment of Acute Upper Respiratory Tract Infections: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2017; 84:54-61. PMID 28761581
88. Stenehjem E, Hyun DY, Septimus E, Yu KC, Meyer M, Raj D, Srinivasan A. Antibiotic Stewardship in Small Hospitals: Barriers and Potential Solutions. Clin Infect Dis 2017; 65:691-696. PMID DOI: 10.1093/cid/cix407
89. Simon GE, Coronado G, DeBar LL, Dember LM, Green BB, Huang SS, Jarvik JG, Mor V, Ramsberg J, Septimus EJ, Staman KL, Vazquez MA, Vollmer WM, Zatzick D, Hernandez AF, Platt R. Data Sharing and Embedded Research. Ann Intern Med 2017; 167:668-670. PMID 28973353
90. Septimus EJ, Coopersmith CM, Whittle J, Hale CP, Fishman NO, Kim TJ. 2017. Sepsis National Hospital Inpatient Quality Measure (SEP-1): Multistakeholder Work Group Recommendations for Appropriate Antibiotics for the Treatment of Sepsis. Clin Infect Dis 2017 65:1565-1569. PMID 29048513
91. Klein EY, Mojica N, Jiang W, Cosgrove SE, Septimus E, Morgan DJ, Laxminarayan R. Trends in Methicillin-Resistant Staphylococcus aureus Hospitalizations in the United States, 2010-2014. Clin Infect Dis 2017; 65:1921-1923. PMID 29020322
92. Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, Kadri SS, Angus DC, Danner RL, Fiore AE, Jernigan JA, Martin GS, Septimus E, Warren DK, Karcz A, Chan C, Menchaca JT, Wang R, Gruber S, Klompas M. Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014. JAMA 2017; 318:1241-1249. PMID 28903154
93. Watson T, Hickok J, Fraker S, Korwek K, Poland RE, Septimus E. . Evaluating the risk factors for hospital-onset Clostridium difficile infections in a large healthcare system. Clin Infect Dis 2017; 66:1957-1959 doi:10.1093/cid/cix1112:cix1112-cix1112.
94. Ostrowsky B, Banerjee R, Bonomo RA, Cosgrove SE, Davidson L, Doron S, Gilbert DN, Jezek A, Lynch IIIJB, Septimus EJ, Siddiqui J, Iovine NM.. Infectious Diseases Physicians: Leading the Way in Antimicrobial Stewardship. Clin Infect Dis 2018; doi:10.1093/cid/cix1093:cix1093-cix1093.
95. Manning ML, Septimus EJ, Ashley ESD, Cosgrove SE, Fakih MG, Schweon SJ, Myers FE, Moody JA. Antimicrobial stewardship and infection prevention-leveraging the synergy: A position paper update. Am J Infect Control 2018; 46:364-368. doi: 10.1016/j.ajic.2018.01.001
96. Nicogossian A, Stabile B, Kloiber O, Septimus E.Addressing Women's Health. World Medical & Health Policy 2018 10:126-128. doi:10.1002/wmh3.269
97. Burgess LH, Miller K, Cooper M, Moody J, Englebright J, Septimus E. Phased implementation of an antimicrobial stewardship program for a large community hospital system. Am J Infect Control 2019; 47:69-73. doi:10.1016/j.ajic.2018.06.009.
98. Rhee C, Jentzsch MS, Kadri SS, Seymour CW, Angus DC, Murphy DJ, Martin GS, Dantes RB, Epstein L, Fiore AE, Jernigan JA, Danner RL, Warren DK, Septimus EJ, Hickok J, Poland RE, Jin R, Fram D, Schaaf R, Wang R, Klompas M,. Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons. Crit Care Med 2019; 47:493-500. DOI 10.1097/ccm.0000000000003554
99. Huang SS, Singh R, McKinnell JA, Park S, Gombosev A, Eells SJ, Gillen DL, Kim D, Rashid S, Macias-Gil R, Bolaris MA, Tjoa T, Cao C, Hong SS, Lequieu J, Cui E, Chang J, He J, Evans K, Peterson E, Simpson G, Robinson P, Choi C, Bailey CC, Leo JD, Amin A, Goldmann D, Jernigan JA, Platt R, Septimus E, Weinstein RA, Hayden MK, Miller LG. Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers. New England Journal of Medicine 2019; 380:638-650. DOI 10.1056/NEJMoa 1716771
100. Memariani A, Gonzales-Luna AJ, Endres BT, Lancaster C, Bassères E, Begum K, Dotson KM, Alam MJ, Garey KW, Sun H, Zhao Z, Walk ST, Offiong C, Arafat R, Tupy S, Kuper K, Septimus E, Hurdle JG, Savidge TC. Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains. Open Forum Infectious Diseases 2019; 6. DOI 10.1093/ofid/ofz013
101. Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Heim L, Gombosev A, Avery TR, Haffenreffer K, Shimelman L, Hayden MK, Weinstein RA, Spencer-Smith C, Kaganov RE, Murphy MV, Forehand T, Lankiewicz J, Coady MH, Portillo L, Sarup-Patel J, Jernigan JA, Perlin JB, Platt R. Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial. The Lancet 2019; 393:1205-1215. doi.org/10.1016/S0140-6736(18)32593-5
Non-peer medical publication
1. Deetz TR, Reves R, Septimus EJ. Secondary rash in toxic shock syndrome. N Engl J Med. 1981; 304; 174 (letter)
2. Septimus EJ, Slama TG. Comparative study of netilmicin and gentamicin in patients with lower respiratory tract infections. Excerpta Medica 1981; 161-162
3. Septimus, EJ. Hepatitis B vaccine use in health care professional. Infect Control 1982; 3:374-376
4. Hamory BH, Safian JQ, Septimus EJ. Employee illness: administrative and medical issues. Conversations in Infection Control. 1985; 6:1-12
5. Septimus EJ. Hepatitis B vaccine: promises and problems. Asepsis 1986; 8:13-15
6. Septimus EJ. Home IV antibiotic therapy: who, when, and how?. Home Health Care in Review. 1988; I:1-4
7. Vartian CV, Septimus EJ. Pyomyositis in an IV drug user with HIV. Arch Intern Med 1988; 148:2689 (letter)
8. Kimbrough III RC, Septimus EJ. Oral antibiotics: a review of use in the outpatient setting. Home Healthcare in Review 1988; IV:1-4
9. Vartian CV. Septimus EJ. Odontogenic infections. J Greater Houston Dental
Soc. 1990; 61:7-8
10. William DN, Septimus EJ. Use of newer devices for home intravenous antibiotic therapy. Home Healthcare in Review 1990; II:1-4
11. Valdez LM, Septimus EJ. Clinical approach to rash and fever. Infect Dis Pract 1996; 20:1-5
12. Septimus EJ. Liver abscess. Infect Dis Practice. 1998; 22:49-50
13. Septimus JD, Septimus EJ. Treatment of serious MRSA infections. Infect Dis Practice 2002; 26:134-136
14. Septimus EJ Treatment of infections due to Nocardia. Infect Dis Practice 2003; 27:315-317
15. Septimus EJ. Automated data mining surveillance:transforming the practice of infection control and prevention. Managing Infect Control 2005; 5:50-52
16. Septimus EJ. Reducing MRSA infections. Managing Infect Control 2007; 7:562-563
17. Septimus EJ. Mandating health care professional influenza vaccination:pro. Infect Dis Children December 2010
Chapters
1. Septimus, EJ, and Reves, R., Osteomyelitis. in Infectious Diseases of Children and Adults, 211-227. Addison-Wesley Publishing Company, Inc., 1986
2. Septimus, EJ, Wallace, RJ, Jr., Nocardial infection. In Current Therapy in Infectious Diseases – 2; 356-357 B.C. Decker, Inc., 1986
3. Septimus EJ. Ambulatory therapy of serious infectious diseases. In Kelley’s Textbook in Internal Medicine, 1819-1821. J.P. Linppincott Co. 1989
4. Septimus EJ, General overview of home intravenous antibiotic therapy. in Recent Advances in Chemotherpay 38: 1-8. E Lewis-Epstein Ltd, 1990
5. Septimus EJ. Ambulatory therapy of serious infectious diseases. In Kelley’s Textbook in Internal Medicine 2nd Edition, 1658-1660. J.P. Linppincott Co. 1992
6. Septimus EJ, Musher DM. Other bacterial infections in the skin. In Infection Color Atlas and Textbook, 50-61. Wiliiams and Wilkins 1995
7. Valdez LM, Septimus EJ. Infections associated with urinary catheters. In Current Therapy Infect Dis 346-348. Mosby 1996
8. Septimus EJ. Osteomyelitis in Conn’s Current Therapy 2004, 1050-1053 Elsevier 2004
9. Septimus EJ. Pleural effusion and empyema. In Mandell, Bennett, & Dolan Principles and Practice of Infectious Diseases. Sixth Edition 854-853 Elsevier 2005
10. Septimus EJ Bacterial pneumonia in Conn’s Current Therapy 2009; 261-264 Elsevier 2009
11. Septimus EJ. Associate editor: Improving medication use and outcomes with clinical decision support. A step by step guide. HIMSS 2009
12. Septimus EJ. Pleural effusion and empyema. In Mandell, Bennett, & Dolan Principles and Practice of Infectious Diseases. Seventh Edition 917-924 Elsevier 2009
13. Septimus EJ Bacterial pneumonia in Conn’s Current Therapy 2009; 336-339 Elsevier 2012
14. Septimus EJ. Pleural effusion and empyema in Decision Support in Medicine 2012
15. Septimus EJ Bacterial pneumonia in Conn’s Current Therapy 2009; 348-351 Elsevier 2014
16. Septimus EJ. Pleural effusion and empyema. In Mandell, Douglas and Bennett, Principles and Practice of Infectious Diseases. Seventh Edition 847-859 Elsevier 2015
17. Septimus EJ Quality and infection prevention: partnering for improved outcomes in Decision Support in Medicine 2017
18. Septimus EJ Bacterial pneumonia in Conn’s Current Therapy 2017; 768-771 Elsevier 2017
19. Septimus EJ. Universal MRSA/Staphyloccal decolonzation for hospitalized patients in Infection Prevention; New Perspectives and Controversies.83-91 Springer 2018
20. Septimus EJ. Bacterial pneumonia in Conn’s Current Therapy 2018; 794-797 Elsevier 2018
Abstracts: Oral and Poster Presentation
1. Septimus, E.J, Wallace, RJ, Jr., Musher, DM., and Martin, RR., Comparison of agar dilutions with a disc diffusion method for antimicrobial susceptibility testing of Nocardia Annual American Society for Microbiology (ASM) meeting 1976
2. Septimus EJ. Holmes, TM., Wende, RD., Musher, DM., and Martin, RR. Antibiotic susceptibility of multi-drug resistant Klebsiella pneumoniae Regional American College of Physicians (ACP) meeting 1976
3. Wallace RJ Jr., Septimus EJ, Vance PH, Weissfeld AS, Martin RR. Beta-lactamase production in ampiciillin-resitance isolates of Nocardia. Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) 1977
4. Wallace RJ, Jr. Septimus EJ, Musher DM, Martin RR. Hemophilus influenzae pneumonia in adults. ICAAC 1977
5. Wallace RJ, Bigby T, Septimus EJ,. The activity of sulfonamides against Mycobacterium fortuitum and Mycobacteium cheloni. ICAAC 1979
6. Septimus, EJ. Nocardia in the compromised host. American Thoracic Society (ATS) Meeting, 1981
7. Wallace, RJ, Jr., Wiss, K., Septimus, EJ, Dalovisio, R. The in-vitro activity of antibacterial agents against Mycobacterium marinum. ATS Meeting, 1981
8. Peninger M., Rex JH, Septimus, E.J., Cost benefit of a silver alloy hydrogel-coated latex urinary catheter in a large healthcare system. APIC 2001
9. El Sahly, HM, Septimus EJ, Reich RA, Soini H, Septimus J, Graviss EA. Mycobacterium simiae pseudo-outbreak resulting from contaminated hospital water supply in Houston, Texas. IDSA 2001
10. Mohr, JF., Peymann, PJ, Kenton, I, Septimus, E., and Okhuysen PC. A retrospective comparative evaluation of dysglycemia in patients receiving fluoroquinolones. Amercian College of Clinical Pharmacy 2005
11. Iversen N, Mellgren J, Baxter C, Septimus E. Prevalence of MRSA colonization: a patient and employee study in a 270-bed regional referral hospital. APIC Meeting 2007
12. Beekmann S, Talbot T, Septimus E, Helms C, Polgreen P. Use of influenza vaccination declination statement in 17 US hospitals. IDSA Meeting 2017
13. Iversen NJ, Mellgren-Backford J, Nightingale C, Saberhagen C, Septimus E. Hospital-wide decrease in MRSA after an intervention in a community hospital. Society for Healthcare Epidemiology of America (SHEA) meeting 2009
14. Perlin J, Septimus E, Englebright J, Moody J, Hickok J. A multi-pronged approach to reduce MRSA in community hospitals. SHEA meeting 2009
15. Perlin J, Septimus E, Englebright J, Moody J, Hickok J. Implementing evidenced-based strategies for reducing MRSA transmission and infections to improve patient outcomes in community hospitals. National Patient Safety Foundation(NPSF) meeting 2009
16. Cormier S, Septimus E, Moody J, Perlin J. Implementation of a successful seasonal influenza vaccine strategy in a large healthcare system. Decennial meeting 2010
17. Perlin J, Septimus E, Englebright J, Moody J, Hickok J. MRSA colonization among high-risk surgical patients in a large community hospital system. Decennial meeting 2010
18. Perlin J, Septimus E, Englebright J, Moody J, Hickok J. Using an automated electronic tracker to aid in meeting NPSG 07.03.01: reduce the risk of HAIs: preventing multi-drug resistant organism (MDRO) infections. NPSF meeting 2010
19. Moody J, Hickok J, Perlin J, Septimus E Decreased healthcare associated C. difficile infections in a large community hospital system thru standardized practices. SHEA meeting 2011
20. Moody J, Septimus E, Hickok, Perlin J. Sustained reduction in healthcare associated MRSA infections using a multi-pronged approach in a large community hospital system. SHEA meeting 2011
21. Hayden MK, Lolans K, Haffenreffer K, Avery TR, Kleinman K, Lankiewicz J, Moody J, Septimus E, Weinstein RA, Hickok J, Jernigan J, Perlin JB, Platt R, Huang SS. CHG susceptibility of MRSA isolates from a multi-state study of adult ICU. SHEA meeting 2011
22. Hickok J, Moody J, Englebright J, Perlin J, Septimus E. Horizontal effects of implementing a vertical MRSA prevention bundle: experience of a large community hospital system and sustained reduction of healthcare associated central line associated bloodstream infections and ventilator associated pneumonia in adult ICUs. IDSA meeting 2011
23. Cormier S, Moody J, Hickok J, Perlin J, Septimus E. Preventing the flu in you: a three-year experience of sustained seasonal influenza vaccination rate in healthcare workers. APIC meeting 2012
24. Huang S, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R. Randomized evaluation of decolonization vs. universal clearance to eliminate MRSA in ICUs. ID Week meeting 2012
25. Uslan DZ, Kelesidis T, Braykov N, Morgan D, Johannson B, Schweizer M, Weisenberg SA, Young H, Cantey, J, Perencevich E, Septimus E, Srinivasan A, Laxminarayan R. Indications and types of antibiotic use in 6 acute care hospitals: results from a cross-sectional study. ID Week meeting 2012
26. Weisenberg SA, Braykov N, Schweizer M, Morgan D, Johannson B, Kelesidis T, Uslan DZ, Young H, Cantey J, Perencevich E, Srinivasan A, Septimus E, Laxminarayan R. Prior antibiotic allergies and adverse reactions: results from a multicenter cross-sectional study. ID Week meeting 2012
27. Morgan D, Johannson B, Schweizer M, Braykov N, Weisenberg SA, Uslan DZ, Kelesidis T, Young H, Cantey J, Septimus E, Srinivasan A, Perencevich E, Laxminarayan R. Frequency of antibiotic de-escalation over six US hospitals: results from a multicenter cross-sectional study. ID Week meeting 2012
28. Bienvenu S, Moody J, Septimus E, Hickok J. Optimizing infection prevention resources through standardization of workflow integrated with infection prevention software. APIC meeting 2013
29. Burgess LH, Septimus EJ, Moody J, Hickok JD, Frost C, Englebright J, Implementation of a comprehensive antimicrobial management program in a large health system. NPSF meeting 2013
30. Robinson SB, Davis SL, Harris AD, Septimus EJ, Bowdy BD, Davis TE, Bumpass B, Culshaw DL, DePestel DD, Kauf TL, Rachfal A. Assessing the burden of S aureus bacteremia using a large multi-hospital database. ID Week 2013
31. Lolans K, Haffenreffer K, Avery T, Kleinman K, Kaganov RE, Lankiewicz J, Moody J, Septimus E, Weinstein RA, Hickok J, Jernigan J, Perlin J, Platt R, Huang S. CHG and mupirocin susceptibility of MRSA isolates in the REDUCE MRSA trial. ID Week meeting 2014
32. Schweizer M, Chiang H-Y, Septimus E, Moody J, Braun B, Hafner J, Ward MA, Hickok J, Perencevich EN, Diekema DJ, Richards CL, Cavanaugh JE, Perlin J, Herwaldt LA. A Multicenter Intervention to Reduce Surgical Site Infections among Patients Undergoing Cardiac Operations and Total Joint Arthroplasty (STOP SSI Study) ID Week meeting 2014
33. Reisinger H, Dukes K, Schweizer M, Braun B, Hafner J, Moody J, Ward MA, Richards C, Hickok J, Septimus E, Perlin J, Herwaldt L. Facilitators and barriers to SSI bundle implementation in select surgical procedures.ID Week meeting 2014
34. Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Heim L, Gombosev A, Avery TR, Haffenreffer K, Shimelman L, Hayden MK, Weinstein RA, Spencer-Smith C, Kaganov RE, Murphy M, Forehand T, Lankiewicz J, Coady M, Portillo L, Sarup-Patel J, Jernigan JA, Poland R, Perlin J, Platt R. Daily Chlorhexidine Bathing in General Hospital Units – Results of the ABATE Infection Trial (Active BAThing to Eliminate Infection) ID Week meeting 2017
35. Septimus E, Versporten A, Goossens H. The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance: Results of Antimicrobial Prescribing in US Hospitals. ECCMID Annual Meeting 2018
36. Rhee C, Jentzsch MS, Kadri SS, Seymour CW, Angus DC, Murphy DJ, Martin GS, Dantes RB, Epstein L, Fiore AE, Jernigan JA, Danner RL, Warren DK, Septimus EJ, Hickok J, Poland RE, Jin R, Fram D, Schaaf R, Wang R, Klompas M,. Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons. ID Week Annual Meeting 2018
37. Pena K, Cooper M, Greer N, Elders T, Septimus E. Procalcitonin Current State Evaluation with a Large Health-System. ID Week Annual Meeting 2018
38. Lubarda J, Maeglin J, Mathews D, Delk T, Septimus E. A Clinical Practice Assessment on Clostridium difficile infection. ID Week Annual Meeting 2018
39. Lin K, Dempsey C, Patel S, Butler J, Septimus E. Evaluating the Impact of Procalcitonin on Antibiotic Utilization in Chronic Obstructive Pulmonary Disease Exacerbations. ID Week Annual Meeting 2018
40. Lubarda J, Maeglin J, Mathews D, Delk T, Septimus E. Prevention and Management: An Assessment of Current Clinical Practice Patterns of Physicians. International C. difficile Symposium (ICDS) 2018